[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644604":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":13,"responsibleParty":33,"collaborators":10,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":41,"acronym":10,"eligibilityCriteria":42,"healthyVolunteers":39,"sex":43,"minAge":44,"maxAge":10,"enrollmentInfo":45,"targetDuration":10,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":56,"overallStatus":16,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization","OTHER",[8,11],{"label":9,"type":10,"description":9,"interventionNames":10},"Reintubation group",null,{"label":12,"type":10,"description":12,"interventionNames":10},"No reintubation group",[14],{"facility":15,"status":16,"city":17,"state":18,"zip":19,"country":20,"countryCode":10,"cosmosGeoPoint":21,"geoPoint":26,"contacts":27},"Prof. Dr. Cemil Taşçıoğlu Şehir Hastanesi","RECRUITING","Istanbul","Şişli","34360","Turkey (Türkiye)",{"type":22,"coordinates":23},"Point",[24,25],28.94966,41.01384,{"lat":25,"lon":24},[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Zekeriya Ervatan","CONTACT","+9005055983248","zek.ervatan@gmail.com",{"type":34,"investigatorFullName":35,"investigatorTitle":36,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Reyhan Kucuk Erturk","Dr.","100644604","assessment-of-reintubation-risk-using-multiple-parameters-in-postoperative-intensive-care-unit-patients-100644604",false,"NCT07672106","Assessment of Reintubation Risk Using Multiple Parameters in Postoperative Intensive Care Unit Patients","Inclusion Criteria:\n\nAdult patients aged 18 years and older\n\nPatients requiring postoperative intensive care follow-up after major surgery, including abdominal, vascular, orthopedic, or ear, nose, throat, head and neck surgery\n\nPatients extubated in the operating room and admitted to the intensive care unit with spontaneous breathing\n\nPatients without any clinical condition preventing the planned measurements within the first 0-2 hours after ICU admission (T0 and T1)\n\nPatients for whom written informed consent can be obtained from the patient or legally authorized representative\n\nPatients admitted to the intensive care unit within the specified study period after ethics committee approval and enrolled consecutively\n\nExclusion Criteria:\n\nPatients younger than 18 years of age\n\nPatients who leave the operating room intubated or are admitted to the intensive care unit while intubated\n\nPatients with a tracheostomy\n\nPatients with a history of diaphragmatic paralysis\n\nPatients with a significant neuromuscular disease, such as ALS, myasthenia gravis, or similar conditions\n\nPatients with conditions that significantly prevent ultrasound measurements, including marked subcutaneous emphysema, large dressings or bandages covering the measurement area, inability to access the measurement site due to drains or the surgical field, or inability to obtain technically adequate images\n\nPatients in whom the planned measurements cannot be performed due to clinical instability requiring emergency intubation immediately after ICU admission\n\nPatients from whom informed consent cannot be obtained, or patients or legally authorized representatives who refuse participation","ALL","18 Years",{"count":46,"type":47},600,"ESTIMATED","OBSERVATIONAL","This prospective, non-interventional observational study will evaluate the risk of reintubation in adult postoperative patients admitted to the intensive care unit after major surgery. Reintubation after extubation is an important clinical problem because it may increase complications, prolong mechanical ventilation, and extend intensive care and hospital stay.\n\nThe study will include adult patients who are extubated in the operating room and admitted to the intensive care unit with spontaneous breathing. Within the first hours after ICU admission, bedside ultrasound measurements of diaphragm thickness, parasternal intercostal muscle thickness, and lung ultrasound score will be performed. The ROX index will also be calculated using oxygen saturation, inspired oxygen concentration, and respiratory rate. Perioperative fluid balance will be recorded from anesthesia and patient files.\n\nPatients will be followed for 48 to 72 hours after ICU admission to determine whether reintubation is required. The study aims to assess whether respiratory muscle ultrasound findings, lung ultrasound score, ROX index, and perioperative fluid balance can help predict reintubation risk in postoperative ICU patients. No additional treatment or intervention will be applied as part of the study, and all clinical decisions will be made by the responsible intensive care team according to routine clinical practice.",[51,52,53,54,55],"Postoperative Respiratory Failure","Extubation Failure","Lung Ultrasonography Score","Diaphragm Thickness","Parasternal Intercostal Muscle Thickness",[57,58,59,51],"lung ultrasonography score","Diaphragm thickness","parasternal intercostal muscle thickness","2026-06-22",{"date":62,"type":63},"2026-06-26","ACTUAL",{"date":65,"type":63},"2026-04-28",{"date":67,"type":47},"2026-10-28",{"name":5,"class":6},1]