[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471140":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":10,"centralContacts":39,"locations":48,"responsibleParty":65,"collaborators":10,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":10,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":10,"enrollmentInfo":78,"targetDuration":10,"studyType":81,"phases":10,"briefSummary":82,"conditions":83,"keywords":10,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Vanderbilt University Medical Center","OTHER",[8,14,18,22,26,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort A",null,"normal eyes with no ocular disease",[13],"Other: Eye swab",{"label":15,"type":10,"description":16,"interventionNames":17},"Cohort B","primary open angle glaucoma\u002FOcular hypertension defined as mild glaucoma which is well controlled with no more than one drop of prostaglandin use daily for the past 6 months",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Cohort C","non-infectious keratopathy not using any prescription medication (OTC artificial tears are acceptable)",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Cohort D","Dry AMD (age related macular degeneration)",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Cohort E","Wet AMD",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Cohort F","diabetic retinopathy, any stage",[13],[35],{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":10},"Eye swab","This is a simple swab under the eyelids of both eyes",[9,15,19,23,27,31],[40,45],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Havin Abdulkadir","CONTACT","6159361474","havin.e.abdulkadir@vumc.org",{"name":46,"role":42,"phone":10,"phoneExt":10,"email":47},"Saige Priddy","saige.priddy@vumc.org",[49],{"facility":5,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Nashville","Tennessee","37232","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-86.78444,36.16589,{"lat":60,"lon":59},[63],{"name":64,"role":42,"phone":10,"phoneExt":10,"email":10},"Sapna Gangaputra, M.D.",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Sapna Gangaputra","Assistant Professor","100471140","assessment-of-the-ocular-microbiome-in-health-and-disease-100471140",false,"NCT05414994","Assessment of the Ocular Microbiome in Health and Disease","Inclusion Criteria:\n\nWe will include subjects who meet all of the following criteria:\n\n* 18 years of age or older\n* Provide informed consent\n* Cohort A - normal eyes with no ocular disease\n* Cohort B - primary open angle glaucoma\u002FOcular hypertension defined as mild glaucoma which is well controlled with no more than one drop of prostaglandin use daily for the past 6 months\n* Cohort C - non-infectious keratopathy not using any prescription medication (OTC artificial tears are acceptable)\n* Cohort D - Dry AMD (age related macular degeneration)\n* Cohort E - Wet AMD\n* Cohort F - diabetic retinopathy\n\nExclusion Criteria:\n\nWe will exclude subjects who meet all of the following criteria:\n\n* Prior ocular disease either of the anterior or posterior segment\n* Any medical comorbidities except well controlled DH and HTN\n* Unable to follow up with study procedures as described",true,"ALL","18 Years",{"count":79,"type":80},500,"ESTIMATED","OBSERVATIONAL","The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and assess the ocular microbiome's role in the health of the anterior segment. We will conduct a prospective, observational cohort study, including a longitudinal analysis of the ocular microbiome in adults.",[84,85,86],"Microbial Colonization","Eye Diseases","Ophthalmopathy","2026-01-19",{"date":89,"type":90},"2026-01-22","ACTUAL",{"date":92,"type":90},"2023-09-07",{"date":94,"type":80},"2027-12-30",{"name":5,"class":6},1]