[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550911":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":22,"centralContacts":27,"locations":10,"responsibleParty":36,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":10,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":10,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":10},{"fullName":5,"class":6},"Sohag University","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"40 adults categorized as MASLD patients",null,[12],"Diagnostic Test: Pro-Neurotensin level as a Serum Biomarker",{"label":14,"type":10,"description":10,"interventionNames":15},"40 adults of non-MASLD (controls)",[12],[17],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DIAGNOSTIC_TEST","Pro-Neurotensin level as a Serum Biomarker","Pro-Neurotensin mediates the development of fatty liver disease. Neurotensin (NT) is a 13-amino acid peptide secreted by the neuroendocrine cells of the small intestine in response to fat ingestion, which facilitates fatty acid absorption through the gut in relation to food lipid content.",[9,14],[23],{"name":24,"affiliation":25,"role":26},"Reem Mahmoud, lecturer","Sohag","STUDY_DIRECTOR",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"omneya deyaa, MD","CONTACT","01126826122","omnia_aboalwafa@med.sohag.edu.eg",{"name":34,"role":30,"phone":35,"phoneExt":10,"email":10},"Khairy Hammam, professor","01003064022",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Omnia Aboelwafa","MD","100550911","assessment-the-diagnostic-value-of-pro-neurotensin-as-a-serum-biomarker-in-masld-100550911",false,"NCT06453239","Assessment the Diagnostic Value of Pro-Neurotensin as a Serum Biomarker in MASLD","Assessment the Diagnostic Value of Pro-Neurotensin as a Serum Biomarker in Metabolic Dysfunction-associated Steatotic Liver Disease","Inclusion Criteria:\n\n* Asymptomatic adults were randomly recruited from relatives of patients in Tropical Medicine and Gastroenterology Outpatient Clinic or the Inpatient Section of the department. Participants were categorized as MASLD patients if their abdominal US examination showed the criteria of fatty liver as described later or Non-MASLD (Controls) if they did not show these criteria.\n\nExclusion Criteria:\n\n* (i) Patients aged \\\u003C18 years or \\>75 years. (ii) History of Alcohol consumption. (iii) A diagnosis of liver diseases other than MASLD, including viral hepatitis, drug-induced liver injury, clinically suspected cases of autoimmune liver disease, Wilson's diseases, primary biliary cholangitis.\n\nThe control group had no illness to cause any inflammation; no usage of alcohol, drug, or herbal substances; no history of previous liver diseases; and was negative for viral hepatitis serology tests and had completely normal liver US.",true,"ALL","18 Years","75 Years",{"count":52,"type":53},80,"ESTIMATED","OBSERVATIONAL","To assess the diagnostic significance of serum pro-NT in MASLD and ability to differentiate between early and advanced steatosis.",[57],"Steatosis of Liver","NOT_YET_RECRUITING","2024-06-05",{"date":61,"type":62},"2024-06-11","ACTUAL",{"date":64,"type":53},"2024-07",{"date":66,"type":53},"2025-08",{"name":5,"class":6}]