[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605029":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":10,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":10,"enrollmentInfo":25,"targetDuration":10,"studyType":28,"phases":10,"briefSummary":29,"conditions":30,"keywords":33,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"adult patients with a confirmed diagnosis of SLE,",null,"Eligible participants are adults (at least 18 years old) diagnosed with SLE according to ACR or SLICC criteria, who have not used antibiotics or proton pump inhibitors in the past four weeks, and provide written informed consent . Of those eligible, the expected sample size is 115 patients, calculated to power the main outcome analysis.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Wanees Ebrahim","resident at the Internal Medicine department","100605029","associating-gastric-infection-with-autoimmune-flare-severity-in-an-egyptians-100605029",false,"NCT07157202","Associating Gastric Infection With Autoimmune Flare Severity in an Egyptians","Association Between Helicobacter Pylori Infection and Disease Activity in Patients With Systemic Lupus Erythematosus (SLE)","Inclusion Criteria:\n\n* Adult patients (aged ≥18 years) with a confirmed diagnosis of SLE according to the American College of Rheumatology (ACR) or Systemic Lupus International Collaborating Clinics (SLICC) classification criteria.\n\nPatients who provide written informed consent to participate in the study. Patients who have not received antibiotics or proton pump inhibitors (PPIs) in the four weeks\n\nExclusion Criteria:\n\n* Patients with a history of gastric surgery or known gastrointestinal malignancy.\n\n  * Patients currently receiving immunosuppressive therapy for conditions other than SLE.\n  * Patients with coexisting autoimmune diseases other than SLE.\n  * Pregnant or lactating women.\n  * Patients with active infections (other than H. pylori) at the time of enrollment.","ALL","18 Years",{"count":26,"type":27},115,"ESTIMATED","OBSERVATIONAL","A cross-sectional, observational study aims to evaluate the relationship between Helicobacter pylori infection and disease activity in patients diagnosed with systemic lupus erythematosus (SLE), using a combination of structured patient interviews, standardized disease assessments, and laboratory detection of H. pylori by stool antigen testing .",[31,32],"H. Pylori","SLE - Systemic Lupus Erythematosus",[34,35],"SLE","H. pylori infection","NOT_YET_RECRUITING","2025-08-28",{"date":39,"type":40},"2025-09-05","ACTUAL",{"date":42,"type":27},"2026-08-30",{"date":44,"type":27},"2027-12-30",{"name":5,"class":6}]