[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575149":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":21,"locations":26,"responsibleParty":44,"collaborators":7,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":7,"enrollmentInfo":56,"targetDuration":7,"studyType":59,"phases":7,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University of Sao Paulo General Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Galectin-3 dosage","Peripheral blood sample will be collected in the 24h before CABG",[14,18],{"name":15,"affiliation":16,"role":17},"Leticia Carvalho","Instituto do Coração - HCFMUSP","PRINCIPAL_INVESTIGATOR",{"name":19,"affiliation":16,"role":20},"Eduardo Lima","STUDY_DIRECTOR",[22],{"name":19,"role":23,"phone":24,"phoneExt":7,"email":25},"CONTACT","+ 5511 26615352","eduglima@yahoo.com.br",[27],{"facility":28,"status":29,"city":30,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Instituto do Coração - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo","RECRUITING","São Paulo","05403000","Brazil","BR",{"type":35,"coordinates":36},"Point",[37,38],-46.63611,-23.5475,{"lat":38,"lon":37},[41],{"name":42,"role":23,"phone":43,"phoneExt":7,"email":25},"Eduardo Gomes Lima, PhD","551126615352",{"type":45,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100575149","association-between-galectin-3-and-post-operative-atrial-fibrillation-after-coronary-artery-bypass-graft-100575149",false,"NCT06768528","Association Between GalectiN-3 and POSt-operative AtrIal Fibrillation After Coronary Artery BypaSs Graft","Association Between Galectin-3 and Post-operative AtrIal Fibrillation After Coronary Artery Bypass Graft","GNOSIS","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass graft surgery\n\nExclusion Criteria:\n\n* Inability to sign the free and informed consent form\n* Renal dysfunction with estimated glomerular filtration rate less than 30ml \u002F min \u002F 1.73m² or dialysis therapy\n* Moderate to severe left ventricular dysfunction (ejection fraction \\\u003C 40%)\n* Patients with previous atrial fibrillation\n* Pregnancy\n* Concomitant valve surgery","ALL","18 Years",{"count":57,"type":58},90,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG). The main question\\[s\\] it aims to answer are:\n\n* Is Galectin-3 an accurate biomarker to predict higher risk of developing post-operative atrial fibrillation?\n* Are high levels of Galectin-3 associated to other post-operative complications and major adverse cardiovascular events? Participants will be enrolled during pre-operative evaluation and a peripheral blood sample collection will be performed in the 24h before CABG. Participants will then be followed for a period of 12 months (daily during hospitalization and 3 appointments after hospital discharge) to determine whether patients with higher levels of Galectin-3 will have worse outcomes.",[62,63,64],"Post-operative Atrial Fibrillation","Cardiovascular Diseases","Post-pericardiotomy Syndrome",[66,67],"Post-operative atrial fibrillation","Galectin-3","2025-01-06",{"date":70,"type":71},"2025-01-10","ACTUAL",{"date":73,"type":71},"2023-01-01",{"date":75,"type":58},"2026-12-01",{"name":5,"class":6},1]