[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100454522":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":22,"centralContacts":26,"locations":31,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":10,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Group 1",null,[12],"Device: local cerebral oxygen saturation",{"label":14,"type":10,"description":10,"interventionNames":15},"Group 2",[12],[17],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"DEVICE","local cerebral oxygen saturation","minimum SctO2, SctO2 drop\u002Frise defined by different thresholds, and area under\u002Fabove the threshold",[9,14],[23],{"name":24,"affiliation":5,"role":25},"Yuming MD Peng, Ph.D","PRINCIPAL_INVESTIGATOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","8610-59976658","florapym766@163.com",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Beijing Tian Tan Hospital, Capital Medical University","RECRUITING","Beijing","Beijing Municipality","100160","China","CN",{"type":41,"coordinates":42},"Point",[43,44],116.39723,39.9075,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":29,"phoneExt":10,"email":30},"Yuming Peng",{"type":25,"investigatorFullName":48,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Prof.","100454522","association-between-local-cerebral-oxygenation-monitoring-and-postoperative-delirium-in-carotid-endarterectomy-100454522",false,"NCT05198635","Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy","Association Between Local Cerebral Oxygen Saturation Monitoring and Postoperative Delirium in Carotid Endarterectomy：A Prospective Cohort Study","Inclusion Criteria:\n\nScheduled carotid endarterectomy; Signed informed consent.\n\nExclusion Criteria:\n\nSevere cognitive impairment(Mini-Mental State Examination, MMSE\\\u003C18); History of psychotropic drugs; Previous intracranial surgery history; Poor hearing or vision; Language barriers","ALL",{"count":60,"type":61},140,"ESTIMATED","OBSERVATIONAL","Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive dysfunction, some also had a history of stroke, and the circulation fluctuated greatly during the operation, often resulting in hypoperfusion of cerebral tissue and hypoxia. Therefore, they're the high-risk group of POD. Near-infrared Spectroscopy (NIRS) can continuously and noninvasively monitor local cerebral oxygen saturation (SctO2) to identify the mismatch of oxygen supply and demand in brain tissue. However, for CEA patients, the association between intraoperative SctO2 changes and POD remains unclear. This study intends to explore the association between them and determine the SctO2 threshold for predicting POD. We will monitor SctO2 intraoperatively, follow up and collect data postoperatively.",[65,66,67],"Cerebral Oxygen Saturation","Postoperative Delirium","Carotid Endarterectomy","2025-02-12",{"date":70,"type":71},"2025-02-13","ACTUAL",{"date":73,"type":71},"2022-02-14",{"date":75,"type":61},"2025-12-31",{"name":5,"class":6},1]