[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602161":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":49,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":75,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group",null,"Normal healthy volunteers aged \\> 30 years",[13],"Genetic: genotyping assay by polymerase chain reaction",{"label":15,"type":10,"description":16,"interventionNames":17},"Experimental Group","Patients aged \\>30 years and diagnosed with Primary Open Angle Glaucoma",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"GENETIC","genotyping assay by polymerase chain reaction","Blood sample will be obtained from all participants by withdrawing 3 mL of blood via venipuncture in ethylenediaminetetraacetic acid tube.\n\nThereafter, DNA extraction will be obtained after centrifugation to be used for genotyping assay of MMP-9 gene with polymerase chain reaction",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Thomas Talaat Nageh, Demonstrator","CONTACT","20 1276890796","thomas.talaat@med.sohag.edu.eg",[31],{"facility":32,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Sohag University Hosipital","Sohag","Sohag Governorate","82525","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],31.69478,26.55695,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":47,"phoneExt":10,"email":48},"Magdy Mohamed Amin El Kady, Professor","( 093 ) 4602963","portal@med.sohag.edu.eg",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Thomas Talaat Nageh","Demonstrator","100602161","association-between-matrix-metalloproteinase-9-gene-polymorphism-and-susceptibility-to-primary-open-angle-glaucoma-patients-in-sohag-university-hospital-100602161",false,"NCT07119905","Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital","Inclusion Criteria:\n\n* Men and women older than 30 years\n* Primary open angle glaucoma as evidenced from characteristic visual field loss and optic disc cupping (POAG group)\n* Healthy subjects matched by age, sex and ethnicity to the POAG patients group (control group)\n\nExclusion Criteria:\n\n* Exfoliation glaucoma, pigmentary glaucoma\n* History of acute angle closure",true,"ALL","30 Years",{"count":63,"type":64},80,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the potential association between MMP-9 gene polymorphism and susceptibility to Primary Open Angle Glaucoma development in Egyptian patients The main question it aims to",[68],"Primary Open Angle Glaucoma (POAG)",[70,71,72,73,74],"Primary Open Angle Glaucoma","POAG","Gene Polymorphism","MMP-9","Matrix Metalloproteinase-9 Gene Polymorphism","NOT_YET_RECRUITING","2025-08-06",{"date":78,"type":79},"2025-08-13","ACTUAL",{"date":81,"type":64},"2026-06-01",{"date":83,"type":64},"2027-02-01",{"name":5,"class":6},1]