[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578304":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":23,"locations":10,"responsibleParty":29,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":10,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":10,"enrollmentInfo":41,"targetDuration":10,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":49,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":10},{"fullName":5,"class":6},"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"EEG (electroencephalogram) monitoring of Parkinson's patients undergoing deep brain stimulation",null,"Parkinson's patients undergoing deep brain stimulation (DBS). Patients will undergo DBS according to institutional protocol and monitoring via EEG will be used to detect burst suppression signals. Patients will undergo cognitive testing via completion of the 3D CAM (3-minute diagnostic interview for confusion assessment method-defined delirium) tool within 15 minutes of arriving to the surgical recovery area after the completion of surgery, discharge from the recovery area, and 24 hours postoperatively. The patients' MoCA (Montreal Cognitive Assessment) score would also be assessed at 24 hours postoperatively.",[13],"Other: EEG (electroencephalogram) monitoring of Parkinson's patients undergoing deep brain stimulation",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"Parkinson's patients undergoing deep brain stimulation (DBS) will be monitored with EEG to detect burst suppression signals during surgery and will undergo postoperative cognitive testing for postoperative delirium.",[9],[19],{"name":20,"affiliation":21,"role":22},"Sujoy Banik, MD","Western University, London Health Sciences Centre","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":27,"email":28},"CONTACT","5196858500","13546","sujoy.banik@lhsc.on.ca",{"type":22,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Sujoy Banik","Anesthesiologist, Assistant Professor","100578304","association-of-eeg-parameters-with-postoperative-delirium-in-patients-with-parkinsons-disease-100578304",false,"NCT06809556","Association of EEG Parameters with Postoperative Delirium in Patient's with Parkinson's Disease","Association of Processed Electroencephalography Derived Parameters with Postoperative Delirium in Patients with Parkinson's Disease Undergoing Elective Neurosurgery","Inclusion Criteria:\n\n1. Diagnosis of Parkinson's disease\n2. Elective neurosurgery for implantation of DBS electrodes and implantable pulse generator (IPG) device.\n3. 18 years of age or older\n\nExclusion Criteria:\n\n1. Refusal\u002Fwithdrawal of consent\n2. Inability to place sensor\u002F record EEG for the entire duration of surgery\n3. Emergency surgery\n4. Redo surgery\n5. Preoperative delirium (defined as per 3D CAM score)","ALL","18 Years",{"count":42,"type":43},40,"ESTIMATED","OBSERVATIONAL","Patients with Parkinson's disease seem prone to developing postoperative delirium after surgery, the causes of which remain understudied and multifactorial. Anesthetic management remains challenging due to the changes in neurotransmitter levels in these patients which translate to altered drug effects. Avoiding excessive anesthesia is essential. Processed electroencephalography (EEG) is used worldwide along with our centre to monitor depth of anesthesia. It is non-invasive and easy to use. Some EEG patterns like \"burst suppression\" are easily identifiable and indicate that the brain has fallen into an excessively low metabolic state, which could mean increased anesthetic sensitivity. Appearance of \"burst suppression\" can predict delirium in non-neurosurgical procedures, but this has never been studied during surgery for deep brain stimulator insertion in Parkinson's disease patients. Through this study we wish to observe the association of EEG parameters with the development of postoperative delirium in this subset of the population.This has the capacity to change anesthetic practice by being mindful of the fragile brain of such patients and individualizing drug dosing for each patient to improve outcomes and reduce hospital stay.",[47,48],"Post Operative Delirium","Parkinson Disease",[50,51,52],"post operative delirium","Parklinson's Disease","EEG","NOT_YET_RECRUITING","2025-01-30",{"date":56,"type":57},"2025-02-05","ACTUAL",{"date":59,"type":43},"2025-03-01",{"date":61,"type":43},"2027-03-31",{"name":5,"class":6}]