[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100490067":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":28,"locations":38,"responsibleParty":61,"collaborators":10,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":10,"enrollmentInfo":73,"targetDuration":76,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":10,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Magdi Yacoub Heart Foundation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control",null,"Healthy Egyptian individuals to provide the first of its kind resource on human genetic variation in Egyptians, which is essential for understanding the significance of detected variations in patients with inherited cardiovascular disease and their families.",[13],"Other: Whole Genome Sequencing to compare healthy volunteers genome with that of cardiomyopathies patients.",{"label":15,"type":10,"description":16,"interventionNames":17},"Cases","Egyptian patients and their family members diagnosed with different types hereditary cardiomyopathies.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Whole Genome Sequencing to compare healthy volunteers genome with that of cardiomyopathies patients.","Egyptian patients and their family members diagnosed with different types hereditary cardiomyopathies.Healthy Egyptian individuals to provide the first of its kind resource on human genetic variation in Egyptians, which is essential for understanding the significance of detected variations in patients with inherited cardiovascular disease and their families.",[15,9],[24],{"name":25,"affiliation":26,"role":27},"Magdi H Yacoub, FRS OM","Imperial College London, and Magdi Yacoub Heart Foundation","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Yasmine Aguib, PhD","CONTACT","+201092036368","yasmine.aguib@aswanheartcentre.com",{"name":35,"role":31,"phone":36,"phoneExt":10,"email":37},"Ahmed Elguindy, MD","+201001615151","ahmed.elguindy@aswanheartcentre.com",[39],{"facility":40,"status":41,"city":42,"state":10,"zip":10,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Aswan Heart Centre - Magdi Yacoub Heart Foundation","RECRUITING","Aswān","Egypt","EG",{"type":46,"coordinates":47},"Point",[48,49],32.89942,24.09082,{"lat":49,"lon":48},[52,55,59],{"name":53,"role":31,"phone":36,"phoneExt":10,"email":54},"Ahmed M ElGuindy, MD, MRCP","ahmed_elguindy@hotmail.com",{"name":56,"role":31,"phone":57,"phoneExt":10,"email":58},"Shehab M Anwer, MD","+41788816333","shehabanwer@gmail.com",{"name":60,"role":27,"phone":10,"phoneExt":10,"email":10},"Magdi H Yacoub, OM FRS",{"type":62,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100490067","aswan-heart-centre---egyptian-healthy-volunteers-100490067",false,"NCT05661305","Aswan Heart Centre - Egyptian Healthy Volunteers","AHC-EHVol","* Inclusion Criteria:\n\n  * Any adult Egyptian citizen subject that considers him\u002Fherself free of cardiovascular disease.\n* Exclusion Criteria:\n\n  * Individuals under 18 years of age\n  * Known cardiovascular disease\n  * Known collagen vascular disease\n  * Individuals with communication difficulties, or who do not wish to participate\n  * Pregnancy\n  * Contraindication to MRI\n  * Family history of sudden death\n  * Family history of a familial cardiomyopathy\n  * Family history of premature coronary artery disease (males \\\u003C40 years, females \\\u003C50 years).\n* Withdrawal Criteria:\n\n  * Withdrawal of consent.",true,"ALL","18 Years",{"count":74,"type":75},1000,"ESTIMATED","5 Years","OBSERVATIONAL","To define the genotype of a healthy Egyptian cohort as a crucial step in determining the possible clinical implications of mutations detected in patients recruited in the registry.",[80],"Genetic Predisposition to Disease","2022-12-14",{"date":83,"type":84},"2022-12-22","ACTUAL",{"date":86,"type":84},"2019-01-01",{"date":88,"type":75},"2030-01-31",{"name":5,"class":6},1]