[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563489":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":31,"responsibleParty":47,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":20,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":20,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":20,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Medical University of South Carolina","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task Specific Training","EXPERIMENTAL","Task-specific training (TST) paired with EMG activated Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) three times a week for two weeks in an At-Home setting.",[13],"Device: Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Remote Transcutaneous Auricular Vagal Nerve Stimulation Paired with Task-Specific Training","Each participant will complete 2 weeks, 3 times per week, task-specific training paired with transcutaneous auricular vagal nerve stimulation.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Bashar Badran, PhD","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":20,"email":30},"Katie Tucker","CONTACT","843-792-9502","tuckekat@musc.edu",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Charleston","South Carolina","29403","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-79.93275,32.77632,{"lat":43,"lon":42},[46],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":20},{"type":48,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[50],{"name":51,"class":52},"National Institute of General Medical Sciences (NIGMS)","NIH","100563489","at-home-tavns---stroke-rehab-100563489",false,"NCT06616831","At-Home taVNS - Stroke Rehab","Development of At-Home Transcutaneous Auricular Vagus Nerve Stimulation for Post-Stroke Rehabilitation","Inclusion Criteria:\n\n* 18-80 years old with an ischemic or hemorrhagic stroke that occurred ≥6 months prior;\n* Ability to give consent;\n* Unilateral limb (left or right) weakness with Fugl Meyer-Upper Extremity Scale score of 19-53\u002F60 points which indicates adequate arm\u002Fhand use for rehabilitation tasks;\n* active wrist flexion\u002Fextension ≥10° with active abduction\u002Fextension of thumb and at least 1 digit ≥10° to further assure ability to participate in rehabilitation tasks;\n* Passive range of motion in affected shoulder, elbow and wrist within 20 degrees of normal values.\n\nExclusion Criteria:\n\n* Other concomitant neurological disorders affecting upper extremity motor function;\n* Presence of Dysphagia or aspiration difficulties;\n* Prior injury to vagus nerve;\n* Pregnancy;\n* Documented history of dementia before or after stroke;\n* Documented history of uncontrolled depression or psychiatric disorder either before or after stroke which could affect their ability to participate in the experiment;\n* Uncontrolled hypertension;\n* Botox injections within 4 weeks of the first day of rehabilitation therapy.","ALL","18 Years","80 Years",{"count":64,"type":65},5,"ESTIMATED","INTERVENTIONAL",[68],"NA","Early evidence suggests the benefits of post-stroke motor rehabilitation may be enhanced by applying electrical stimulation to the ear. This study aims to test the new approach of pairing ear stimulation with motor rehabilitation in the home setting in stroke survivors with upper limb motor function deficits.",[71,72,73],"Stroke","Stroke, Ischemic","Stroke Hemorrhagic","2025-05-15",{"date":76,"type":77},"2025-05-20","ACTUAL",{"date":79,"type":77},"2024-10-28",{"date":81,"type":65},"2026-09-30",{"name":5,"class":6},1]