[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528723":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":10,"locations":29,"responsibleParty":53,"collaborators":56,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Catania","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Control",null,"Healthy patients between 20 and 40 years",[13,14],"Diagnostic Test: Auditory test","Other: CSF sampling",{"label":16,"type":10,"description":17,"interventionNames":18},"MS group","Patient with Relapsing Remitting MS age between 20 and 40 years",[13,14],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"DIAGNOSTIC_TEST","Auditory test","The patients will perform:\n\nPure Tone Auditory test + Tympanometry and Stapedial Reflex\n\n* Speech Perception test\n* In case of tinnitus: tinnitus questionnaire and acuphenometry\n* DPOAEs\n* ABR",[9,16],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"CSF sampling","Cerebrospinal Fluid will be collected by lumbar puncture and analyzed",[9,16],[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Arianna Di Stadio","RECRUITING","Catania","Sicily","95121","Italy","IT",{"type":39,"coordinates":40},"Point",[41,42],15.07041,37.49223,{"lat":42,"lon":41},[45,50],{"name":46,"role":47,"phone":48,"phoneExt":10,"email":49},"Arianna Di Stadio, MD, PhD","CONTACT","095\u002F123546","ariannadistadio@hotmail.com",{"name":51,"role":52,"phone":10,"phoneExt":10,"email":10},"Athanasia Warnecke, MD, PhD","SUB_INVESTIGATOR",{"type":54,"investigatorFullName":31,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Associate Professor fixed time",[57],{"name":58,"class":6},"Hannover Medical School","100528723","auditory-functions-in-patients-with-multiple-sclerosis-100528723",false,"NCT06164483","Auditory Functions in Patients With Multiple Sclerosis","Electrophysiological Studies of Auditory Functions and CSF Analyses in Patients With Multiple Sclerosis","Inclusion Criteria\n\n* age \\>18 and \\\u003C50,\n* no history of hearing loss,\n* no psychiatric condition\n* no familial history of otosclerosis\u002Fdeafness\u002Fgenetic hearing loss\n* patients with PD and\u002For MS.\n\nExclusion Criteria\n\n* Conductive hearing loss\n* stroke \\\u003C 2 years\n* cardiovascular disease non under control\n* diabetes\n* hypotensive disorders\n* alcohol abuse\n* recreational drug consumption\n* epilepsy",true,"ALL","20 Years","40 Years",{"count":71,"type":72},30,"ESTIMATED","OBSERVATIONAL","The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test, speech perception test, Auditory Brain Response (ABR) and Distortion Product Otoacustic Emission (DPOAE). CSF will be collected by lumbar puncture and analyzed looking for inflammatory markers.\n\nThe results of DPOAE and CSF will be correlated to identify statistically significant correlation.",[76,77],"Multiple Sclerosis","Hearing Disorders","2026-05-11",{"date":80,"type":81},"2026-05-12","ACTUAL",{"date":78,"type":81},{"date":84,"type":72},"2028-12-30",{"name":5,"class":6},1]