[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590983":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":37,"responsibleParty":50,"collaborators":24,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":78,"whyStopped":24,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Hôpital le Vinatier","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patient group with a first episode psychosis","EXPERIMENTAL","Tasks will include an auditory localization task performed in virtual reality, a source-monitoring task, an externalization task and a battery of psychoacoustic tests.",[13],"Behavioral: cognitive experiments' session",{"label":15,"type":16,"description":11,"interventionNames":17},"Healthy control subjects","ACTIVE_COMPARATOR",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","cognitive experiments' session","The aim of this unique session of cognitive experiments is to study the auditory localization performance in patients with a first episode of psychosis. Results of this Arm 1 will be compared to those of Arm 2.",[15,9],null,[26],{"name":27,"affiliation":28,"role":29},"Frédéric HAESEBAERT, university professor","hopital le Vinatier","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":35,"email":36},"Lydie SARTELET, Sponsor project manager","CONTACT","0437915531","+33","lydie.sartelet@ch-le-vinatier.fr",[38],{"facility":39,"status":24,"city":40,"state":24,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":24},"Centre hospitalier le Vinatier","Bron","69678","France","FR",{"type":45,"coordinates":46},"Point",[47,48],4.91303,45.73865,{"lat":48,"lon":47},{"type":51,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100590983","auditory-localization-in-schizophrenia-100590983",false,"NCT06974513","Auditory Localization in Schizophrenia","Auditory Localization in Virtual Reality in Patients With a First Episode of Psychosis","LOCIZ","Inclusion Criteria:\n\n* Informed of the study and having signed the consent form\n* With normal vision (with or without correction)\n* Able to understand the experimental instructions\n* Affiliated to the social security system\n* French language spoken, read and written\n\nExclusion Criteria:\n\n* Patients with a DSM-5 diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder or brief psychotic disorder\n* Early intervention for first psychotic episodes",true,"ALL","18 Years","35 Years",{"count":65,"type":66},60,"ESTIMATED","INTERVENTIONAL",[69],"NA","Auditory sound localization is the ability to identify the position of a sound source in space. It is defined into 3 dimensions: by its position in azimuth, elevation and distance. If it is difficult to localize a sound source, it is possible to remove the localization ambiguity by interacting with the environment, in particular by changing one's position in relation to the source (e.g. by changing the orientation of the head).\n\nPatients with schizophrenia have difficulties to localize and discriminate sounds in space but it is still poorly explored.\n\nAdditionally, deficits in auditory localization could underlie difficulties in source-monitoring (i.e., distinguish the source\u002Forigin of the information) reported in schizophrenia or deficits in auditory externalization (i.e., perception of sound outside the head).\n\nFurthermore, schizophrenia is characterized by cerebral abnormalities in the auditory cortex, manifesting as auditory processing disorders at different stages of the pathology. Auditory localization may therefore be impaired from the onset of a first psychotic episode (FEP). This early phase of the disease is also referred to as the \"critical\" period, as the chances of remission are highest and the response to treatment is best. However, the three-dimensional aspect of auditory perception and the behavioral exploration strategies used to localize a sound in the early stages of schizophrenia are still little studied.",[72],"Auditory Perception",[74,75,76,77],"Localization","Auditory perception","Source monitoring","Virtual reality","NOT_YET_RECRUITING","2025-05-07",{"date":81,"type":82},"2025-05-16","ACTUAL",{"date":84,"type":66},"2025-06-30",{"date":86,"type":66},"2028-06",{"name":5,"class":6},1]