[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533789":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":34,"responsibleParty":50,"collaborators":12,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":12,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":12,"enrollmentInfo":63,"targetDuration":12,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":12,"overallStatus":36,"whyStopped":12,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Aarhus University Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","Patients will be operated with a standard exploratory PTX, with visual identification of PTGs. Unilateral or bilateral parathyroid exploration will be determined by the surgeon, depending on preoperative imaging and intraoperative findings. Usually, the procedure will be terminated when intraoperative parathyroid hormone (PTH) measurement shows a \\>50% decline, after removal of suspected pathological PTGs.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Surgery with EleVision IR camera system","EXPERIMENTAL","Patients randomized to the experimental group will have surgery performed in the exact same manner as in the control group.\n\nIn the experimental group, the surgeon will use the EleVision IR camera system (Medtronic, USA) to visualize PTGs during surgery. The surgical field will be visualized with AF as a minimum of two times during surgery on each side of the neck: First upon exposing the undersurface of the thyroid gland, and secondly before removal of a pathological PTG. Also, removed PTGs will be examined ex vivo to document AF pattern.",[18],"Procedure: Surgery with autofluorescence",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","Surgery with autofluorescence","In the experimental group, the surgeon will use the EleVision IR camera system (Medtronic, USA) to visualize PTGs during surgery. The surgical field will be visualized with AF as a minimum of two times during surgery on each side of the neck: First upon exposing the undersurface of the thyroid gland, and secondly before removal of a pathological PTG. Also, removed PTGs will be examined ex vivo to document AF pattern.",[14],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Jacob K Lilja-Fischer, MD","CONTACT","+4540460399","jaclil@rm.dk",{"name":32,"role":28,"phone":12,"phoneExt":12,"email":33},"Lars Rolighed, MD,PhD","larsroli@rm.dk",[35],{"facility":5,"status":36,"city":37,"state":12,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Aarhus","8200","Denmark","DK",{"type":42,"coordinates":43},"Point",[44,45],10.21076,56.15674,{"lat":45,"lon":44},[48],{"name":49,"role":28,"phone":29,"phoneExt":12,"email":30},"Jacob Kinggaard Lilja-Fischer, MD",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Jacob Kinggaard Lilja-Fischer","MD, Associate Professor","100533789","autofluorescence-in-surgery-for-primary-hyperparathyroidism-100533789",false,"NCT06230380","Autofluorescence in Surgery for Primary Hyperparathyroidism","Use of Intraoperative Autofluorescence Imaging in Surgery for Primary Hyperparathyroidism - a Randomized Controlled Trial.","Inclusion Criteria:\n\n* Age\\>18 years and able to give informed consent.\n* A diagnosis of PHPT.\n* Planned exploratory PTX with ioPTH measurement.\n\nExclusion Criteria:\n\n* Concordant high-confidence imaging; planned focused\u002Fselective PTX\n* Previous thyroid or parathyroid surgery.\n* Planned simultaneous thyroid surgery.\n* MEN, lithium induced hyperparathyroidism.\n* eGFR \\\u003C 30.\n* Kidney transplant.","ALL","18 Years",{"count":64,"type":65},100,"ESTIMATED","INTERVENTIONAL",[68],"NA","The study aims to test if autofluorescence imaging (AF) is a useful surgical aid during parathyroidectomy (PTX) for primary hyperthyroidism (PHPT).",[71],"Hyperparathyroidism, Primary","2025-01-27",{"date":74,"type":75},"2025-01-29","ACTUAL",{"date":77,"type":75},"2024-01-01",{"date":79,"type":65},"2026-06-01",{"name":5,"class":6},1]