[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641052":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":26,"centralContacts":34,"locations":43,"responsibleParty":62,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":10,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":78,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":86,"overallStatus":92,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Cumhuriyet University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Autologous Free Dermal Graft Group",null,"Participants undergoing primary bilateral superior pedicle vertical scar reduction mammaplasty with placement of a de-epithelialized autologous free dermal graft in the lower pole region as part of routine surgical practice. No study-specific surgical assignment or randomization will be performed.",[13],"Procedure: Autologous Free Dermal Graft Support",{"label":15,"type":10,"description":16,"interventionNames":10},"No Free Dermal Graft Group","Participants undergoing primary bilateral superior pedicle vertical scar reduction mammaplasty without placement of an autologous free dermal graft. This group will receive the same basic reduction mammaplasty technique according to routine surgical practice, without study-specific surgical assignment or randomization.",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"PROCEDURE","Autologous Free Dermal Graft Support","Placement of a de-epithelialized autologous free dermal graft in the lower pole region during superior pedicle vertical scar reduction mammaplasty. The dermal graft is obtained from the participant's own de-epithelialized skin during the planned breast reduction procedure and is used as an autologous structural support method. The graft is not vascularized and does not remain attached to a dermal or glandular pedicle. No synthetic or biological mesh material is used.",[9],[24,25],"Autologous dermal graft support","Free dermal graft lower pole support",[27,31],{"name":28,"affiliation":29,"role":30},"Handan Derebaşınlıoğlu","Cumhuriyet University","STUDY_DIRECTOR",{"name":32,"affiliation":29,"role":33},"Murat Çelik, Assistant Professor","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":10,"email":38},"CONTACT","+905546902104","mucetr@gmail.com",{"name":40,"role":36,"phone":41,"phoneExt":10,"email":42},"Handan Derebaşınlıoğlu, Associate Professor","90 346 487 00 00","handanderebasinlioglu@gmail.com",[44],{"facility":45,"status":10,"city":46,"state":46,"zip":47,"country":48,"countryCode":10,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Sivas Cumhuriyet University","Sivas","58050","Turkey (Türkiye)",{"type":50,"coordinates":51},"Point",[52,53],37.01611,39.74833,{"lat":53,"lon":52},[56,58,59,60],{"name":32,"role":36,"phone":57,"phoneExt":10,"email":38},"05546902104",{"name":40,"role":36,"phone":41,"phoneExt":10,"email":42},{"name":32,"role":33,"phone":10,"phoneExt":10,"email":10},{"name":40,"role":61,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":33,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Murat Çelik","Assistant Professor","100641052","autologous-free-dermal-graft-support-in-superior-pedicle-vertical-scar-reduction-mammaplasty-100641052",false,"NCT07657962","Autologous Free Dermal Graft Support in Superior Pedicle Vertical Scar Reduction Mammaplasty","Effect of Autologous Free Dermal Graft Use on Lower Pole Stability in Superior Pedicle Vertical Scar Reduction Mammaplasty: A Prospective Comparative Cohort Study","Inclusion Criteria:\n\n* Female participants aged 18 to 65 years\n* Planned primary bilateral reduction mammaplasty\n* Planned use of the superior pedicle vertical scar technique\n* Willingness to attend at least 6 months of postoperative follow-up\n* Ability to provide written informed consent\n* Consent for standardized medical photography and clinical breast measurements\n\nExclusion Criteria:\n\n* Previous breast surgery\n* Oncoplastic breast reduction\n* Unilateral reduction mammaplasty\n* Use of a pedicle technique other than the superior pedicle\n* Use of a scar pattern other than the vertical scar pattern\n* Presence of a systemic condition expected to significantly impair wound healing\n* Active smoking within the last 6 weeks before surgery\n* Incomplete 6-month follow-up data for the primary outcome analysis","FEMALE","18 Years","65 Years",{"count":76,"type":77},70,"ESTIMATED","6 Months","OBSERVATIONAL","The goal of this observational study is to learn whether using an autologous free dermal graft during breast reduction surgery helps maintain lower breast pole shape over time in women undergoing primary bilateral reduction mammaplasty.\n\nThe main question it aims to answer is:\n\nDoes autologous free dermal graft support reduce lower pole lengthening between 1 month and 6 months after surgery?\n\nResearchers will compare two groups of participants. One group will undergo superior pedicle vertical scar reduction mammaplasty with autologous free dermal graft support as part of routine surgical care. The other group will undergo the same basic breast reduction technique without autologous free dermal graft support.\n\nParticipants will:\n\n* Have their planned breast reduction surgery as part of routine care\n* Attend postoperative follow-up visits at 1, 3, and 6 months\n* Have standard breast measurements and medical photographs taken during follow-up\n* Complete a breast satisfaction questionnaire at 6 months",[82,83,84,85],"Breast Ptosis","Mammaplasty","Lower Pole Elongation","Postoperative Breast Pseudoptosis",[87,88,89,90,91],"Reduction mammaplasty","Superior pedicle","Autologous free dermal graft","Vertical scar reduction mammaplasty","Aesthetic outcome","NOT_YET_RECRUITING","2026-06-14",{"date":95,"type":96},"2026-06-18","ACTUAL",{"date":98,"type":77},"2026-08-01",{"date":100,"type":77},"2028-02-01",{"name":5,"class":6},1]