[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100439135":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":52,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":19,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":33,"whyStopped":19,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Washington","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Transplantation","EXPERIMENTAL","Endovascular infusion",[13],"Other: Endovascular autologous mitochondrial transplantation",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Endovascular autologous mitochondrial transplantation","During standard-of-care endovascular reperfusion procedure, subjects will have autologous mitochondria infused via microcatheter into ischemic brain.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Melanie S Walker, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Study Coordinator","CONTACT","206-897-5802","sanslab@uw.edu",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Harborview Medical Center","RECRUITING","Seattle","Washington","98104","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-122.33207,47.60621,{"lat":43,"lon":42},[46,49],{"name":47,"role":27,"phone":48,"phoneExt":19,"email":19},"Melanie Walker, MD","206-744-3000",{"name":50,"role":51,"phone":19,"phoneExt":19,"email":19},"Michael Levitt, MD","SUB_INVESTIGATOR",{"type":23,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Melanie Walker","Professor, School of Medicine","100439135","autologous-mitochondrial-transplant-for-cerebral-ischemia-100439135",false,"NCT04998357","Autologous Mitochondrial Transplant for Cerebral Ischemia","Study Title: Autologous Mitochondrial Transplant for Cerebral Ischemia","Inclusion Criteria:\n\n* Eligible for endovascular thrombectomy to treat acute large vessel occlusion\n* Eligible for angioplasty (microcatheter-based balloon\u002Fmechanical and chemical angioplasty) to treat acute cerebral vasospasm after aneurysmal subarachnoid hemorrhage\n* Subjects for whom there is likely to be enough time to obtain meaningful consent from patient or legally-authorized representative\n\nExclusion Criteria:\n\n* Unable to receive a brain MRI scan\n* Known mitochondrial disease\n* Hemodynamically unstable patients in whom standard of care endovascular reperfusion treatment cannot safely be performed or completed","ALL","18 Years","85 Years",{"count":66,"type":67},20,"ESTIMATED","INTERVENTIONAL",[70],"NA","The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.",[73],"Cerebral Ischemia",[75,76],"autologous mitochondrial transplantation","ischemic stroke","2025-05-15",{"date":79,"type":80},"2025-05-21","ACTUAL",{"date":82,"type":80},"2021-04-29",{"date":84,"type":67},"2026-10-29",{"name":5,"class":6},1]