[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100323874":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":32,"responsibleParty":49,"collaborators":19,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":19,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":35,"whyStopped":19,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of Pittsburgh","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Ovarian tissue transplant","EXPERIMENTAL","Transplantation of ovarian tissue into the abdomen. Only for patients who have previously frozen ovarian tissue",[13],"Procedure: Ovarian tissue transplant",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","Pieces of previously frozen ovarian cortex will be put in the abdomen laparoscopically, or with mini laparotomy",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Kyle Orwig, PhD","University of Pittsburgh\u002FUniversity of Pittsburgh Medical Center","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Jennifer Anglin","CONTACT","412-641-7475","1","fertilitypreservation@upmc.edu",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Magee-Womens Hospital","RECRUITING","Pittsburgh","Pennsylvania","15213","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-79.99589,40.44062,{"lat":45,"lon":44},[48],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},{"type":24,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Kyle Orwig","Professor","100323874","autologous-ovarian-tissue-transplantation-100323874",false,"NCT03496636","Autologous Ovarian Tissue Transplantation","Inclusion Criteria:\n\n* Previously cryopreserved ovarian tissue\n* Ovarian insufficiency and\u002For candidate for pregnancy\n* Good health\n* Oncologist's clearance\n\nExclusion Criteria:\n\n* Patients considered to be high risk for surgical complications\n* Women with contraindication for pregnancy if goal is to achieve pregnancy\n* Women positive for the BRCA mutations\n* Women with a history of leukemia, ovarian cancer or a cancer that likely involved ovaries at the time of ovarian tissue collection\n* Women with psychological, psychiatric, or other conditions which prevent giving fully informed consent\n* Current pregnancy","FEMALE","18 Years","45 Years",{"count":62,"type":63},5,"ESTIMATED","INTERVENTIONAL",[66],"NA","Chemotherapy and radiation for cancer and other conditions can cause infertility. Several centers around the world are cryopreserving ovarian tissue from these patients though an experimental protocol, including the Fertility Preservation Program in Pittsburgh (protocol PRO08050491). The objective of this study is to study the efficacy and safety of autologous tissue transplantation in patients diagnosed with primary ovarian insufficiency after chemotherapy and\u002For radiation treatments.",[69],"Female Infertility",[71,72],"Ovary","Transplant","2025-08-12",{"date":75,"type":76},"2025-08-14","ACTUAL",{"date":78,"type":76},"2021-03-01",{"date":80,"type":63},"2027-09-01",{"name":5,"class":6},1]