[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619835":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":34,"responsibleParty":50,"collaborators":12,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":12,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":12,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":37,"whyStopped":12,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Bakirkoy Dr. Sadi Konuk Research and Training Hospital","OTHER_GOV",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group","NO_INTERVENTION","Participants assigned to the control group will receive standard intraoperative mechanical ventilation according to institutional practice during general anesthesia for laparoscopic colorectal surgery. No lung recruitment maneuvers will be performed. Perioperative monitoring, anesthetic management, and postoperative care will be standardized and identical to those of the intervention group, except for the application of automated lung recruitment maneuvers.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Automated Recruitment Group","EXPERIMENTAL","Participants in the intervention group will receive standard intraoperative mechanical ventilation plus automated lung recruitment maneuvers performed by the anesthesia ventilator. The automated recruitment protocol will be applied twice: once after induction of anesthesia and before the initiation of pneumoperitoneum, and once again after pneumoperitoneum is terminated. All other anesthetic management, monitoring, and postoperative care will be identical to the control group.",[18],"Procedure: Automated Intraoperative Lung Recruitment Maneuvers",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"PROCEDURE","Automated Intraoperative Lung Recruitment Maneuvers","Automated lung recruitment maneuvers will be performed intraoperatively using the anesthesia ventilator in pressure-controlled ventilation mode according to a standardized protocol.",[14],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Sena Gökçe Karataş","CONTACT","+90 212 414 71 71","senagokce_96@outlook.com",{"name":32,"role":28,"phone":29,"phoneExt":12,"email":33},"Evrim Kucur Tülübaş","kucurevrim@gmail.com",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":12,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi","RECRUITING","Istanbul","Bakırkoy","34147","Turkey (Türkiye)",{"type":43,"coordinates":44},"Point",[45,46],28.94966,41.01384,{"lat":46,"lon":45},[49],{"name":12,"role":28,"phone":29,"phoneExt":12,"email":12},{"type":51,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100619835","automated-intraoperative-lung-recruitment-maneuvers-in-major-laparoscopic-surgery-100619835",false,"NCT07349784","Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery","Effect of Automated Intraoperative Lung Recruitment Maneuvers on Atelectasis in Patients Undergoing Major Laparoscopic Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Scheduled for elective laparoscopic colorectal cancer surgery\n* American Society of Anesthesiologists (ASA) physical status I-III\n\nExclusion Criteria:\n\n* ASA physical status IV or higher\n* Pregnancy\n* Body mass index (BMI) \\> 40 kg\u002Fm²\n* Severe chronic obstructive pulmonary disease (COPD), GOLD stage III-IV\n* Advanced heart failure with left ventricular ejection fraction \\\u003C35%\n* Previous thoracic surgery\n* Preoperative requirement for supplemental oxygen therapy\n* Refusal or inability to provide informed consent\n* Intraoperative conversion to open surgery\n* Development of significant hemodynamic instability during lung recruitment maneuvers","ALL","18 Years","80 Years",{"count":63,"type":64},56,"ESTIMATED","INTERVENTIONAL",[67],"NA","Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration. Atelectasis developing during surgery may persist into the postoperative period and contribute to postoperative pulmonary complications. Automated lung recruitment maneuvers delivered by modern anesthesia ventilators may offer a standardized method to improve lung aeration and reduce atelectasis. This prospective, randomized, single-center controlled trial aims to evaluate the effect of automated intraoperative lung recruitment maneuvers on atelectasis detected by lung ultrasonography in patients undergoing elective major laparoscopic colorectal cancer surgery. Adult patients will be randomized to receive either automated lung recruitment maneuvers or standard mechanical ventilation without recruitment. Lung ultrasonography will be used to assess atelectasis at predefined perioperative time points. The primary outcome is the incidence of atelectasis detected by lung ultrasound, and secondary outcomes include postoperative pulmonary complications, length of intensive care unit stay, length of hospital stay, and perioperative hemodynamic instability.",[70,71],"Atelectasis","Postoperative Pulmonary Complications (PPCs)",[73,74,75],"Lung Ultrasound Score (LUS)","Automated Lung Recruitment Maneuvers","Laparoscopic Colorectal Surgery","2026-01-19",{"date":78,"type":79},"2026-01-21","ACTUAL",{"date":81,"type":79},"2025-12-13",{"date":83,"type":64},"2026-12",{"name":5,"class":6},1]