[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608163":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":52,"collaborators":54,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":24,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":24,"overallStatus":37,"whyStopped":24,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Conceivable Life Sciences","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Automated Vitrification","EXPERIMENTAL","Oocytes\u002Fembryos from a particular donor will be randomized to manual or automated vitrification. There will be no randomization at the patient level",[13],"Device: Automated Vitrification",{"label":15,"type":16,"description":11,"interventionNames":17},"Manual Vitrification","ACTIVE_COMPARATOR",[18],"Device: Manual Vitrification",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","The PRESERVE-CR system performs automated vitrification (ultra-rapid freezing) of human oocytes and embryos using robotic manipulation and computer-controlled timing.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Control specimens are vitrified by standard vitrification protocol.",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Giuseppe Silvestri, PhD","CONTACT","+44 7990960731","giuseppe@conceivable.life",[35],{"facility":36,"status":37,"city":38,"state":24,"zip":24,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"CARE Fertility","RECRUITING","Manchester","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-2.23743,53.48095,{"lat":45,"lon":44},[48],{"name":49,"role":31,"phone":50,"phoneExt":24,"email":51},"Tom Bamford, MD, PhD","+44 (0) 800 564 2270","Tom.Bamford@carefertility.com",{"type":53,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[55],{"name":56,"class":57},"CARE Fertility UK","OTHER","100608163","automation-of-oocyte-and-embryo-vitrification-100608163",false,"NCT07197983","Automation of Oocyte and Embryo Vitrification","Automation of Oocyte and Embryo Vitrification: a Pilot Study","Inclusion Criteria:\n\n* BMI: Between 20-35 kg\u002Fm²\n* Ovarian Reserve: Anti-Müllerian Hormone (AMH) ≥1.5 ng\u002FmL\n\nExclusion Criteria:\n\n* Low ovarian reserve\n* Surgical sperm retrieval required","ALL","18 Years","38 Years",{"count":69,"type":70},125,"ESTIMATED","INTERVENTIONAL",[73],"NA","Purpose: This study aims to test whether a new automated system can freeze human eggs and embryos as effectively as the current manual method performed by laboratory staff.\n\nBackground: Currently, freezing eggs and embryos during fertility treatments (IVF\u002FICSI) is done entirely by hand by skilled embryologists. This manual process is time-consuming, requires extensive training, and outcomes can vary between different staff members. Automating this process could help standardize procedures, reduce costs, and potentially make fertility treatments more accessible to patients.\n\nWhat is Being Tested: The study will compare an automated freezing system (prototype designation PRESERVE-CR) against the standard manual freezing method. The key research question is: Can the automated system preserve eggs and embryos as successfully as experienced embryologists do by hand?\n\nHow It Works: Patients undergoing IVF\u002FICSI treatment at CARE Fertility Manchester who consent to participate will have their surplus eggs and embryos (those not suitable for their treatment) divided into two groups. Some will be frozen using the traditional manual method, and some using the new automated system. Both groups will then be thawed to measure survival rates. Tests do not encompass any reproductive outcomes or the creation of embryos specifically for this research.\n\nWhy This Matters: If successful, automated freezing could help reduce the workload on laboratory staff, standardize the freezing process across different clinics, potentially lower treatment costs, and make fertility treatments available to more people who need them. The study only uses oocytes and embryos which are unsuitable for patient treatment and that would otherwise be discarded, ensuring no impact on participants' actual fertility treatment.",[76],"Infertility","2025-11-17",{"date":79,"type":80},"2025-11-20","ACTUAL",{"date":82,"type":80},"2025-10-14",{"date":84,"type":70},"2026-06-30",{"name":5,"class":6},1]