[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526637":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":23,"locations":33,"responsibleParty":49,"collaborators":53,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":18,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":35,"whyStopped":18,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Avocado Group","EXPERIMENTAL","Participants will consume 1 avocado per day and receive education to maintain usual caloric intake for 12 weeks and participate in 4 study visits.",[13],"Other: Avocado Group",{"label":15,"type":16,"description":17,"interventionNames":18},"No Diet Modification Group","NO_INTERVENTION","Participants will continue their normal dietary pattern for 12 weeks and participate in 4 study visits.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":18},"Participants will consume provided avocados daily and track consumption for the duration of the study. Participants will be adding avocados to their diet and will receive education on maintaining usual diet.",[9],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":18,"email":28},"Emma Kelly, MS","CONTACT","913-588-7683","ekelly9@kumc.edu",{"name":30,"role":26,"phone":31,"phoneExt":18,"email":32},"Matthew Taylor, PhD","913-588-5363","mtaylor3@kumc.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Kansas City","Kansas","66160","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-94.62746,39.11417,{"lat":45,"lon":44},[48],{"name":25,"role":26,"phone":27,"phoneExt":18,"email":28},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Matthew Taylor","Dr. Matthew K Taylor, PhD, RD",[54],{"name":55,"class":56},"Avocado Nutrition Center","UNKNOWN","100526637","avocog---the-effect-of-daily-avocado-intake-on-cognitive-function-in-older-adults-100526637",false,"NCT06137339","AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults","AvoCog - The Effect of Daily Avocado Intake on Cognitive Function in Older Adults","AvoCog","Inclusion Criteria:\n\n* Males and females aged 65-85 years\n* Good general health with no concomitant disease\n* BMI 18.5 - 35 kg\u002Fm2\n* Mini Mental State Exam ≥26\n* Reports consuming ≤2 medium avocados per month\n* Reports consuming ≤3 servings of carotenoid-rich foods per week and ≤3 servings of fruits and vegetables per day\n* Skin carotenoid content \\\u003C400\n\nExclusion Criteria:\n\n* Unwilling or unable to consume avocado\n* Latex allergy\n* Consistently taking lutein + zeaxanthin supplements\n* Skin carotenoid content ≥400\n* Central neurological disease such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, brain tumor, etc.\n* Serious medical risk: cancer requiring chemotherapy or radiation within the past 5 years, recent cardiac event (i.e. heart attack, etc.)\n* Diabetes mellitus or uncontrolled hypertension\n* Use of psychoactive or investigational medications\n* Consumption of ≥3 alcoholic drinks per day or substance abuse\n* Unable to undergo MRI",true,"ALL","65 Years","85 Years",{"count":70,"type":71},70,"ESTIMATED","INTERVENTIONAL",[74],"NA","The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.",[77],"Brain Aging",[79,80,81,82,83,84],"Older Adults","Brain Health","Avocado","Brain Imaging","Cognition","Dietary Intervention","2024-08-20",{"date":87,"type":88},"2024-08-22","ACTUAL",{"date":90,"type":88},"2024-04-09",{"date":92,"type":71},"2025-12",{"name":5,"class":6},1]