[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587576":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":39,"responsibleParty":59,"collaborators":32,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":32,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":32,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":32,"overallStatus":41,"whyStopped":32,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Awake thoracic epidural anesthesia group","EXPERIMENTAL","Patients will preoperatively receive awake thoracic epidural anesthesia.",[13],"Drug: Awake thoracic epidural anesthesia",{"label":15,"type":16,"description":17,"interventionNames":18},"General anesthesia group","ACTIVE_COMPARATOR","Patients will receive general anesthesia.",[19],"Drug: General anesthesia",[21,27],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Awake thoracic epidural anesthesia",[9],[26],"Bupivacaine",{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":30},"General anesthesia",[15],[31],"Fentanyl",null,[34],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Mohamed E Abdel Fattah, MD","CONTACT","00201284475792","mohamed-elsaid@cu.edu.eg",[40],{"facility":5,"status":41,"city":42,"state":32,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Cairo","12613","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.24967,30.06263,{"lat":50,"lon":49},[53,54,57],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},{"name":55,"role":56,"phone":32,"phoneExt":32,"email":32},"Samuel F Samy, MD","PRINCIPAL_INVESTIGATOR",{"name":58,"role":56,"phone":32,"phoneExt":32,"email":32},"Mohammed S ElSharkawy, MD",{"type":56,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Mohamed Elsaid Abdel Fattah","Lecturer of Anesthesia, Surgical ICU and Pain Management, Faculty of Medicine, National Cancer Institute, Cairo University, Egypt.","100587576","awake-thoracic-epidural-anesthesia-versus-general-anesthesia-in-thoracotomy-100587576",false,"NCT06930183","Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy","Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 75 years old.\n* Both genders.\n* American Society of Anesthesiologists (ASA) physical status classification II or III.\n* Scheduled for thoracotomy.\n\nExclusion Criteria:\n\n* Difficult airway management,\n* Hemodynamically unstable patients, obesity (body mass index \\>30).\n* Absolute contraindication to thoracic epidural anesthesia such as (patient refusal, allergy to local anesthetics, coagulopathy, active neurologic disorders, skin infection at insertion site, uncooperative patients, uncontrolled cough, and unfavorable anatomy for thoracic epidural).\n* Neurological disorders: risk of seizure, unable to cooperate, intracranial mass or brain edema, extensive pleural adhesions or previous pulmonary resections, hypoxemia (PaO2 \\\u003C60) or hypercarbia (PaCO2 \\>50)\n* Poor cardiac function (ejection fraction less than 50%).\n* Patients with bad pulmonary function tests.","ALL","18 Years","75 Years",{"count":73,"type":74},50,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.",[80,81,82,83],"Awake","Thoracic Epidural Anesthesia","General Anesthesia","Thoracotomy","2025-04-16",{"date":86,"type":87},"2025-04-17","ACTUAL",{"date":84,"type":87},{"date":90,"type":74},"2025-10-01",{"name":5,"class":6},1]