[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570151":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":27,"locations":36,"responsibleParty":50,"collaborators":24,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":24,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":24,"enrollmentInfo":63,"targetDuration":24,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":79,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Microlaryngeal surgery (MLS)","ACTIVE_COMPARATOR","For traditional MLS under general anesthesia, after general anesthesia and intubation with microlaryngeal tube, the patient would be positioned on head-ring support for better alignment and access to glottis. A laryngoscope will be inserted transorally under direct vision and suspended. Vocal cord cysts are visualized with microscope, and removed with microsurgery instruments with microflap technique and sent for routine section. After the surgery, the patient is kept nil-by-mouth until fully awake, and is discharged on same day or the next day depending on the post- operative recovery. Patient will be discharged with voice rest for 3 days.",[13],"Procedure: Microlaryngeal surgery (MLS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Awake transnasal laser-assisted surgery (TNLS)","EXPERIMENTAL","For TNLS, patients are admitted to the day center on the same morning or afternoon of the surgery with fasting prior 6 hours. After local anesthesia application, a 445nm blue laser is introduced via a working channel of bronchoscope and laser ablation of vocal cord cyst is performed. During the operation, patient will receive continuous SpO2 monitoring with regular blood pressure monitoring. After the procedure, patients are kept nil-by-mouth for 2 hours until anesthesia wears off, meanwhile with close observation in day ward with continuous SpO2 monitor for 1 hour. Patients will be discharged on the same day of the procedure, with voice rest for 3 days.",[19],"Procedure: Awake transnasal laser-assisted surgery (TNLS)",[21,25],{"type":22,"name":15,"description":17,"armGroupLabels":23,"otherNames":24},"PROCEDURE",[15],null,{"type":22,"name":9,"description":11,"armGroupLabels":26,"otherNames":24},[9],[28,33],{"name":29,"role":30,"phone":31,"phoneExt":24,"email":32},"Aurora KY Tam, MBBS, MRCSEd","CONTACT","+852-3505 1409","tky369@ha.org.hk",{"name":34,"role":30,"phone":31,"phoneExt":24,"email":35},"Wing Kei Ng","cherrieng@cuhk.edu.hk",[37],{"facility":38,"status":24,"city":39,"state":24,"zip":24,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"The Chinese University of Hong Kong","Hong Kong","HK",{"type":42,"coordinates":43},"Point",[44,45],114.17469,22.27832,{"lat":45,"lon":44},[48],{"name":34,"role":30,"phone":49,"phoneExt":24,"email":35},"+852 35051409",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Tam Aurora Ka Yue","Principal Investigator","100570151","awake-transnasal-laser-assisted-surgery-tnls-and-microlaryngeal-surgery-for-vocal-cord-cyst-100570151",false,"NCT06703515","Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Vocal Cord Cyst","Randomized Controlled Trial of Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Vocal Cord Cyst","Inclusion Criteria:\n\n* Patients with vocal cord cysts\n* older than 18-year-old\n* able to independently provide consent\n* able to tolerate flexible laryngoscopy would be recruited\n\nExclusion Criteria:\n\n* under 18-year-old\n* unable to independently give an informed consent\n* unable to tolerate flexible laryngoscopy\n* allergic to local anesthesia\n* had unfavorable anatomy such as prolapsing epiglottis precluding adequate visualization, extensive lesions and an expected difficult operation as judged by the surgeons\n* with pathologies other than vocal cord cyst","ALL","18 Years",{"count":64,"type":65},54,"ESTIMATED","INTERVENTIONAL",[68],"NA","This is a prospective randomised controlled trial conducted at two tertiary referral hospitals in Hong Kong to compare the clinical and functional outcomes of office-based awake transnasal laser-assisted laryngeal surgery (TNLS) under local anesthesia to traditional microlaryngeal surgery for vocal cord cyst under general anesthesia.",[71],"Vocal Cord Cyst",[73,74,75,76,77,78],"Vocal cord cyst","Transnasal laser surgery","Microlaryngeal surgery","Office based laser surgery","Awake laser laryngeal surgery","Trublue laser","NOT_YET_RECRUITING","2024-11-20",{"date":82,"type":83},"2024-11-25","ACTUAL",{"date":85,"type":65},"2024-12-01",{"date":87,"type":65},"2027-12-31",{"name":5,"class":6},1]