[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100391182":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":21,"responsibleParty":36,"collaborators":38,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":7,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":7,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":24,"whyStopped":7,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"European Breast Cancer Research Association of Surgical Trialists","NETWORK",null,[9],{"name":10,"affiliation":5,"role":11},"Thorsten Kühn, Prof.","STUDY_CHAIR",[13,18],{"name":10,"role":14,"phone":15,"phoneExt":16,"email":17},"CONTACT","+49711 3103-3051","+4971131033051","info@eubreast.com",{"name":19,"role":14,"phone":7,"phoneExt":7,"email":20},"Maggie Banys-Paluchowski, PD Dr.","m.banys@outlook.com",[22],{"facility":23,"status":24,"city":25,"state":7,"zip":7,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Klinikum Esslingen","RECRUITING","Esslingen am Neckar","Germany","DE",{"type":29,"coordinates":30},"Point",[31,32],9.30473,48.73961,{"lat":32,"lon":31},[35],{"name":10,"role":14,"phone":7,"phoneExt":7,"email":7},{"type":37,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[39,42,45,47,49,51],{"name":40,"class":41},"AWOgyn","OTHER",{"name":43,"class":44},"AGO-B","UNKNOWN",{"name":46,"class":41},"North Eastern German Society of Gynaecological Oncology",{"name":48,"class":41},"GBG Forschungs GmbH",{"name":50,"class":44},"Claudia von Schilling Foundation for Breast Cancer Research",{"name":52,"class":44},"Ehmann-Stiftung Savognin","100391182","axillary-surgery-after-neoadjuvant-treatment-100391182",false,"NCT04373655","AXillary Surgery After NeoAdjuvant Treatment","A Prospective Multicenter Cohort Study to Evaluate Different Surgical Methods of Axillary Staging (sentinel Lymph Node Biopsy, Targeted Axillary Dissection, Axillary Dissection) in Clinically Node-positive Breast Cancer Patients Treated with Neoadjuvant Chemotherapy","AXSANA","Inclusion Criteria:\n\n* Signed informed consent form\n* Primary invasive breast cancer (confirmed by core biopsy)\n* cN+\n* cT1-4c\n* Scheduled for neoadjuvant systemic therapy\n* Female \u002F male patients ≥ 18 years old\n\nExclusion criteria\n\n* Distant metastasis\n* Recurrent breast cancer\n* Inflammatory breast cancer\n* Extramammary breast cancer\n* Supraclavicular lymph node metastasis\n* Pregnancy\n* Less than 4 cycles of NACT administered\n* Patients not suitable for surgical treatment","ALL","18 Years",{"count":64,"type":65},3000,"ESTIMATED","5 Years","OBSERVATIONAL","The optimal surgical axillary staging technique in patients who convert from the clinically positive to clinically negative lymph node status under neoadjuvant therapy (cN+ → ycN0) remains to be clarified. Different strategies (axillary lymph node dissection, sentinel node biopsy, targeted axillary dissection) are currently used in different countries. A prospective analysis comparing these techniques regarding feasibility, safety, morbidity and surgical effort is urgently needed. Due to high complexity and discordant recommendations, a randomized trial comparing different techniques is hardly feasible. Therefore, the EUBREAST study group decided to initiate a prospective cohort study as an international project that aims at comparatively evaluating data on axillary staging after neoadjuvant therapy.",[70],"Breast Cancer",[72,73,74,75,76,77],"breast cancer","neoadjuvant chemotherapy","axillary lymph node dissection","targeted axillary dissection","target lymph node","sentinel node biopsy","2025-02-27",{"date":80,"type":81},"2025-03-03","ACTUAL",{"date":83,"type":81},"2020-04-28",{"date":85,"type":65},"2030-04",{"name":5,"class":6},1]