[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626526":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":10,"responsibleParty":29,"collaborators":10,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":37,"eligibilityCriteria":38,"healthyVolunteers":33,"sex":39,"minAge":40,"maxAge":10,"enrollmentInfo":41,"targetDuration":10,"studyType":44,"phases":10,"briefSummary":45,"conditions":46,"keywords":48,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":10},{"fullName":5,"class":6},"University Hospital, Limoges","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Ventilator Associated Pneumonia (VAP)",null,"Patient who developped Ventilator Associated Pneumonia (VAP) under mechanical ventilation",{"label":13,"type":10,"description":14,"interventionNames":10},"Without Ventilator Associated Pneumonia","Patient who did not develop Ventilator Associated Pneumonia (VAP) under mechanical ventilation",[16],{"name":17,"affiliation":5,"role":18},"Julien VAIDIE, Dr","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Safirah Akowanou","CONTACT","+33555058755","safirah.akowanou@chu-limoges.fr",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Abdeslam BEN TALEB","+33555058616","abdeslam.bentaleb@chu-limoges.fr",{"type":30,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100626526","b-lymphocyte-populations-in-the-pulmonary-microenvironment-of-patients-under-mechanical-ventilation-with-or-without-vap-ventilator-associated-pneumonia-100626526",false,"NCT07436780","B Lymphocyte Populations in the Pulmonary Microenvironment of Patients Under Mechanical Ventilation With or Without VAP (Ventilator-Associated Pneumonia)","Pilot Study Describing B Lymphocyte Populations in the Pulmonary Microenvironment of Patients Under Mechanical Ventilation With or Without VAP (Ventilator-Associated Pneumonia)","OLYMPE","Inclusion Criteria:\n\n* Adult patients (≥18 years old), admitted to intensive care under mechanical ventilation for an estimated duration of at least 5 days.\n\nExclusion Criteria:\n\n* Patients admitted for an infectious pneumonia or presenting with acute respiratory distress syndrome (ARDS). Patients in aplasia (leukocytes \\\u003C 0.5 gigal\u002FL).","ALL","18 Years",{"count":42,"type":43},75,"ESTIMATED","OBSERVATIONAL","Diagnosis of VAP relies on a set of non-specific clinical, biological, and imaging criteria.\n\nUnderstanding host-pathogen interactions and the mechanisms of deregulations leading to infection of pulmonary tissue appears essential.\n\nThe aim is to qualitatively describe the B lymphocyte populations present in the pulmonary microenvironment of patients admitted to intensive care and requiring invasive mechanical ventilation",[47],"Ventilator-associated Pneumonia",[49,50,51,52],"ventilator-associated pneumonia","Intensive care medicine","host-pathogen interaction","humoral immunity","NOT_YET_RECRUITING","2026-02-23",{"date":56,"type":57},"2026-02-27","ACTUAL",{"date":59,"type":43},"2026-01-31",{"date":61,"type":43},"2027-07-30",{"name":5,"class":6}]