[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600675":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":48,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Istanbul Saglik Bilimleri University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients diagnosed with endarterectomy",null,[12,13],"Other: atheroma plaque","Other: dental plaque",[15,19],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"atheroma plaque","During the endarterectomy procedure, samples will be collected for study from some of the atheroma plaques routinely taken for pathology from patients.",[9],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"dental plaque","Subgingival plaque samples will be collected from patients before the endarterectomy procedure.",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Ayşe Toraman","CONTACT","05385025422","draysetoraman@gmail.com",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":10,"country":34,"countryCode":10,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Health Sciences University, Hamidiye Faculty of Dentistry, Department of Periodontology","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":36,"coordinates":37},"Point",[38,39],28.94966,41.01384,{"lat":39,"lon":38},[42],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},{"type":44,"investigatorFullName":25,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","associate professor","100600675","bacteria-in-dental-plaque-and-atheroma-plaque-100600675",false,"NCT07100574","Bacteria in Dental Plaque and Atheroma Plaque","Inclusion Criteria:\n\n* Diagnosed with endarterectomy\n* Not receiving chemotherapy\n* Not having received this treatment before\n\nExclusion Criteria:\n\n* Having systemic infection\n* Patients with severe heart disease","ALL","18 Years","85 Years",{"count":56,"type":57},60,"ESTIMATED","OBSERVATIONAL","Periodontitis is considered a focus of infection where oral bacteria, bacterial by-products or inflammatory mediators can interact with other parts of the organism via the blood. Periodontal pathogen components such as DNA, RNA or specific antigens of P. gingivalis, Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), Treponema denticola (T. denticola), Fusobacterium nucleatum (F. nucleatum) or Campylobacter rectus have been isolated from different tissues such as atheroma plaques, placenta, amniotic sac and respiratory tract. It has been reported that periodontitis may contribute to endothelial dysfunction leading to the formation of atherosclerosis.",[61,62,63,64],"Gingival Inflammation","Dental Plaque","Atheroma Plaque","Oral Bacteria","2025-08-01",{"date":67,"type":68},"2025-08-03","ACTUAL",{"date":70,"type":68},"2024-12-10",{"date":72,"type":57},"2026-03-30",{"name":5,"class":6},1]