[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600660":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":37,"responsibleParty":72,"collaborators":75,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":79,"sex":84,"minAge":24,"maxAge":85,"enrollmentInfo":86,"targetDuration":24,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":39,"whyStopped":24,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A (30 seconds)","EXPERIMENTAL","Patients who are randomized into Group A will undergo endoscopic balloon dilation for a total of 30 seconds.",[13],"Procedure: Endoscopic Balloon Dilation",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B (180 seconds)","Patients randomized into Group B will undergo endoscopic balloon dilation for a duration of 180 seconds.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Endoscopic Balloon Dilation","Endoscopic balloon dilation is a routine procedure in which a catheter with a balloon is introduced into the esophagus to help treat esophageal strictures via endoscope. The catheter is placed directly across the span of the esophageal stricture and the balloon is inflated to pre-determined volume in order to dilate the esophageal stricture. Balloon will remain inflated for either 30 or 180 seconds based on patient's randomization.",[9,15],null,[26],{"name":27,"affiliation":5,"role":28},"Jessica Yasuda, MD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","617-355-3038","Jessica.Yasuda@childrens.harvard.edu",{"name":35,"role":31,"phone":24,"phoneExt":24,"email":36},"James Orozco, DO","james.orozco@childrens.harvard.edu",[38,55],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-71.05977,42.35843,{"lat":49,"lon":48},[52,54],{"name":27,"role":31,"phone":24,"phoneExt":24,"email":53},"jessica.yasuda@childrens.harvard.edu",{"name":35,"role":31,"phone":24,"phoneExt":24,"email":36},{"facility":56,"status":39,"city":57,"state":58,"zip":59,"country":43,"countryCode":44,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"Children's Hospital of Philadelphia","Philadelphia","Pennsylvania","19104",{"type":46,"coordinates":61},[62,63],-75.16362,39.95238,{"lat":63,"lon":62},[66,69],{"name":67,"role":31,"phone":24,"phoneExt":24,"email":68},"Michael Manfredi, MD","manfredim@chop.edu",{"name":70,"role":31,"phone":24,"phoneExt":24,"email":71},"Rosa Hwang","HWANGR3@chop.edu",{"type":28,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Jessica Lacy Yasuda","Attending Physician",[76],{"name":56,"class":6},"100600660","balloon-inflation-time-for-esophageal-strictures-bites-a-randomized-multi-center-study-100600660",false,"NCT07100379","Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study","BITES","Inclusion Criteria:\n\n* Diagnosed with esophageal atresia with and without tracheoesophageal fistula, surgically repaired esophageal atresia, esophageal anastomotic strictures requiring endoscopic balloon dilation, and at least 1 endoscopic balloon dilation for esophageal anastomotic strictures within a 6 month period.\n\nExclusion Criteria:\n\n* Patients who need endoscopic incisional therapy to manage anastomotic stricture during their first follow up endoscopy, patients requiring administration of intralesional steroid within 4 weeks of repair, have no follow up endoscopy within 6 months period, have any anastomosis type other than esophago-esophageal (e.g. jejunal or colonic interposition), and\u002For failure to meet target dilation time.","ALL","18 Years",{"count":87,"type":88},128,"ESTIMATED","INTERVENTIONAL",[91],"NA","Esophageal atresia (EA) is one of the most common gastrointestinal congenital anomalies that affects 1 in 2500 to 1 in 4000 live births. It is characterized by abnormal development of the esophagus, which requires surgical intervention to be compatible with life. Surgical repair of EA is associated with risk of developing esophageal strictures or narrowing, which nearly affects 40% of cases. Strictures can be treated using endoscopic balloon dilation, which consists of introducing a catheter with a balloon into the esophagus via endoscopy and positioning it across stricture followed by balloon inflation. The inflated balloon is held in position for a set amount of time with the goal to dilate the narrowed area. At this time there are no pediatric studies comparing difference balloon dilation times and outcomes. Our study's goal is to evaluate balloon dilation inflation time in treating esophageal anastomotic strictures to understand if inflation time is associated with outcome.",[94,95,96],"Esophageal Atresia With Tracheo-esophageal Fistula","Esophageal Atresia","Esophageal Strictures",[98,99,100],"endoscopic balloon dilation","post-surgical correction","esophageal strictures","2026-04-27",{"date":103,"type":104},"2026-04-30","ACTUAL",{"date":106,"type":104},"2025-10-28",{"date":108,"type":88},"2028-06-24",{"name":5,"class":6},2]