[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636053":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":50,"collaborators":52,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":10,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":75,"overallStatus":82,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Koç University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cohort 1: Patients Without Pressure Injury",null,"ICU patients who do not develop pressure injuries during the follow-up period. Skin barrier function parameters (TEWL, pH, stratum corneum hydration, local skin temperature) will be measured longitudinally in pressure injury-prone anatomical regions.",{"label":13,"type":10,"description":14,"interventionNames":10},"Cohort 2: Patients With Pressure Injury","ICU patients who develop pressure injuries during the follow-up period. Skin barrier function parameters will be assessed in both pressure injury-prone regions and adjacent intact skin areas to evaluate changes associated with pressure injury development.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"TUĞBA ERDEM, PhD","CONTACT","+90 532 739 15 01","tyeni@ku.edu.tr",[22],{"facility":5,"status":10,"city":23,"state":10,"zip":24,"country":25,"countryCode":10,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Istanbul","34000","Turkey (Türkiye)",{"type":27,"coordinates":28},"Point",[29,30],28.94966,41.01384,{"lat":30,"lon":29},[33,35,39,42,44,46,48],{"name":17,"role":18,"phone":34,"phoneExt":10,"email":20},"+90 532 739 1501",{"name":36,"role":18,"phone":37,"phoneExt":10,"email":38},"Meryem YILDIZ AYVAZ, PhD","+90 554 379 8373","mayvaz@ku.edu.tr",{"name":40,"role":41,"phone":10,"phoneExt":10,"email":10},"EVREN ŞENTÜRK, PROFESSOR","SUB_INVESTIGATOR",{"name":43,"role":41,"phone":10,"phoneExt":10,"email":10},"EREN AÇIK, Medical Doctor",{"name":45,"role":41,"phone":10,"phoneExt":10,"email":10},"ŞÜKRAN GURA, MSc Nurse",{"name":47,"role":41,"phone":10,"phoneExt":10,"email":10},"MERYEM YILDIZ AYVAZ, PhD",{"name":17,"role":49,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[53],{"name":54,"class":6},"Koc University Hospital","100636053","barrier-functions-of-skin-in-icu-skin-bar-100636053",false,"NCT07560683","Barrier Functions oF Skin in ICU: SKIN-BAR","Investigation of Skin Barrier Function Using Biosensor Methods in Risky Skin Regions and Developed Pressure Injuries in Intensive Care Patients, and Identification of Influencing Factors: The SKIN-BAR Project","SKIN-BAR","Inclusion Criteria:\n\n* Adults aged \\>18 years\n* Admission to the intensive care unit\n* Initial skin assessment completed within the first 4 hours after ICU admission\n* Hemodynamically stable enough to undergo follow-up and repeated skin measurements\n* Intact skin integrity at ICU admission\n* Willingness to participate in the study, with informed consent provided by the participant or legally authorized representative\n\nExclusion Criteria:\n\n* Inability to tolerate position changes\n* Post-cardiopulmonary resuscitation care period at enrollment\n* Cardiac arrest or cardiopulmonary resuscitation during follow-up\n* Severe edema or subcutaneous fluid accumulation\n* Presence of skin lesions before ICU admission\n* Systemic dermatologic disease directly affecting skin barrier function","ALL","18 Years",{"count":66,"type":67},156,"ESTIMATED","OBSERVATIONAL","This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration, local skin temperature, and sebum will be assessed in anatomical regions at risk for pressure injuries. The study will examine temporal changes in these parameters, their interrelationships, and their association with pressure injury development.",[71,72,73,74],"Pressure Injuries","Skin Failure","Skin Abnormalities","Biophysical Parameters of Skin",[76,77,78,79,80,81],"barrier function of skin","pressure-prone skin areas","pressure injury","intensive care unit","biosensory","skin integrity","NOT_YET_RECRUITING","2026-04-28",{"date":85,"type":86},"2026-05-01","ACTUAL",{"date":88,"type":67},"2026-07-01",{"date":90,"type":67},"2028-10-01",{"name":5,"class":6},1]