[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526039":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":25,"locations":35,"responsibleParty":58,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":10,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":10,"enrollmentInfo":73,"targetDuration":76,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":10,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Universitaire Ziekenhuizen KU Leuven","OTHER",[8,13,16],{"label":9,"type":10,"description":10,"interventionNames":11},"Healthy controls",null,[12],"Procedure: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation",{"label":14,"type":10,"description":10,"interventionNames":15},"CRSwNP patients",[12],{"label":17,"type":10,"description":10,"interventionNames":18},"AR patients",[12],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation","Conchotomy involves the reduction or removal of hypertrophic nasal turbinates, aesthetic nose surgery is a surgical procedure that aims to enhance the appearance of the nose, while functional endoscopic sinus surgery is a minimally invasive procedure focused on treating sinus conditions by removing obstructions and improving sinus drainage.",[17,14,9],[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Peter Hellings, MD, PhD","CONTACT","+32 16 33 23 42","peter.hellings@uzleuven.be",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Dominique Bullens, MD, PhD","+32 16 34 13 38","dominique.bullens@uzleuven.be",[36],{"facility":37,"status":38,"city":39,"state":10,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Peter Hellings","RECRUITING","Leuven","3000","Belgium","BE",{"type":44,"coordinates":45},"Point",[46,47],4.70093,50.87959,{"lat":47,"lon":46},[50,54],{"name":51,"role":28,"phone":52,"phoneExt":10,"email":53},"dominique bullens, MD PhD","+3216341338","dominique.bullens@kuleuven.be",{"name":55,"role":28,"phone":56,"phoneExt":10,"email":57},"Daan Rodiers, MsC","+3216346165","daan.rodiers@kuleuven.be",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[61],{"name":62,"class":63},"Regeneron Pharmaceuticals","INDUSTRY","100526039","basal-instincts-towards-better-understanding-of-basal-cell-function-in-chronic-rhinosinusitis-with-nasal-polyps-100526039",false,"NCT06129552","Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps","Inclusion Criteria:\n\n* Patients over the age of 18\n* Males and females\n\nExclusion Criteria:\n\n* CRSwNP\n* AR\n* Smoker, or \\\u003C 1-year ex-smoker\n* Underlying systematic pathology (Morbus Wegener or Churg Strauss Syndrome for example)",true,"ALL","18 Years",{"count":74,"type":75},300,"ESTIMATED","1 Day","OBSERVATIONAL","During this project, the investigators want to explore in vitro changes in basal cells and the crosstalk with residing immune cells as potential pathogenic mechanisms in CRSwNP vs healthy controls by using surgically resected patient samples.",[80,81],"Chronic Rhinosinusitis With Nasal Polyps","Allergic Rhinitis","2024-03-21",{"date":84,"type":85},"2024-03-22","ACTUAL",{"date":87,"type":85},"2023-12-19",{"date":89,"type":75},"2027-12",{"name":5,"class":6},1]