[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100470740":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Suicide attempters\u002Fideations",null,"Patients currently suffering from a major depressive disorder and reporting at least one suicidal event (suicide attempt or hospitalization for suicidal ideation) over the last 12 months.",[13],"Biological: Blood sample",{"label":15,"type":10,"description":16,"interventionNames":17},"Affective controls","Patients currently suffering from a major depressive disorder and reporting no suicidal event (suicide attempt or hospitalization for suicidal ideation) over the last 12 months.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"BIOLOGICAL","Blood sample","Blood sample for the determination of plasma lithium levels",[15,9],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Bénédicte NOBILE, Pharma D, PhD","CONTACT","+33467338581","b-nobile@chu-montpellier.fr",[31],{"facility":32,"status":33,"city":34,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"CHU Montpellier","RECRUITING","Montpellier","France","FR",{"type":38,"coordinates":39},"Point",[40,41],3.87635,43.61093,{"lat":41,"lon":40},[44],{"name":45,"role":27,"phone":10,"phoneExt":10,"email":10},"Benedicte NOBILE",{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100470740","basal-plasma-lithium-levels-and-suicidal-events-100470740",false,"NCT05409794","Basal Plasma Lithium Levels and Suicidal Events","Basal Plasma Lithium Levels and Suicidal Events (LIPS)","LIPS","Inclusion Criteria:\n\n* 18 years old or over\n* Current major depressive episode according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria\n* No lithium-based treatment over the last 12 months\n* For suicide attempters\u002Fideations only : suicidal event over the last 12 months\n* For affective controls only : no suicidal event over the last 12 months\n\nExclusion Criteria:\n\n* Lifetime diagnosis of schizoaffective disorder, schizophrenia or psychosis\n* Pregnancy or breastfeeding\n* Deprivation of freedom (by judicial or administrative decision)\n* Legal protection measure (guardianship or curators)\n* Inability to understand experimental procedures\n* No affiliation to the French National Social Security System\n* No consent to participate in the study","ALL","18 Years",{"count":59,"type":60},158,"ESTIMATED","OBSERVATIONAL","Suicidal behavior is a major public health issue and there are currently no specific treatments for it.\n\nHowever, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.\n\nApart from drug treatments, lithium is present in our environment and its levels varies from one individual to another, depending, especially, on diet.\n\nKnowing that patients with a mood disorder generally have a poor lifestyle and a less rich and varied diet than the general population, variations in basal lithium levels can be expected in these patients.",[64,65,66],"Major Depressive Disorder","Suicidal Behavior","Bipolar Disorder",[68,69,70],"Lithium","Depression","Suicide","2024-08-07",{"date":73,"type":74},"2024-08-09","ACTUAL",{"date":76,"type":74},"2022-12-09",{"date":78,"type":60},"2027-01-09",{"name":5,"class":6},1]