[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619521":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Endovascular Therapy",null,[12],"Procedure: Endovascular Therapy",{"label":14,"type":10,"description":10,"interventionNames":10},"Best Medical Treatment Alone",[16],{"type":17,"name":9,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Endovascular therapy performed as part of routine clinical care for acute basilar artery occlusion, including mechanical thrombectomy with stent retriever and\u002For aspiration. Rescue angioplasty and\u002For intracranial stenting may be used at the operator's discretion. Peri-procedural management and concomitant medical therapy follow local standard practice.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Chuanhui Li","CONTACT","15210439828","lichuanhui@xwh.ccmu.edu.cn",[27],{"facility":28,"status":10,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Xuanwu Hospital","Beijing","Beijing Municipality","100053","China","CN",{"type":35,"coordinates":36},"Point",[37,38],116.39723,39.9075,{"lat":38,"lon":37},[41],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":43,"investigatorFullName":22,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Associate Professor, Xuanwu Hospital, Captimal Medical University","100619521","basilar-artery-occlusion-chinese-endovascular-registry-in-patients-with-large-core-infarct-100619521",false,"NCT07345702","Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct","Endovascular Versus Medical Therapy for Acute Large-Core Basilar Artery Occlusion: A Multicenter Retrospective Registry Study (BAOCHE-LC)","BAOCHE-LC","Inclusion Criteria:\n\n1. Age ≥18 years, men or women.\n2. Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA\u002FMRA\u002FDSA.\n3. Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days.\n4. Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.\n\nExclusion Criteria:\n\n1. Subjects with occlusions in both anterior and posterior circulation.\n2. CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed).\n3. Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset\u002Flast known well time, or missing major treatment information including whether EVT was performed).\n4. Baseline NIHSS score \\\u003C6.\n5. Woman of childbearing potential who is known to be pregnant or lactating or who has a positive pregnancy test on admission.\n6. Missing follow-up outcomes at 90 days.\n7. Any other condition judged by investigators to substantially affect analysis or interpretation.","ALL","18 Years",{"count":56,"type":57},518,"ESTIMATED","OBSERVATIONAL","This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.",[61,62,63],"Basilar Artery Occlusion","Ischemic Stroke","Large Core Infarct","NOT_YET_RECRUITING","2026-01-15",{"date":67,"type":68},"2026-01-20","ACTUAL",{"date":70,"type":57},"2026-01-31",{"date":72,"type":57},"2026-10-31",{"name":5,"class":6},1]