[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636991":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":54,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":11,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":39,"whyStopped":11,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Western Norway University of Applied Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Nitrate rich","EXPERIMENTAL",null,[13],"Dietary Supplement: Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training",{"label":15,"type":16,"description":11,"interventionNames":17},"Nitrate depleted","PLACEBO_COMPARATOR",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"DIETARY_SUPPLEMENT","Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training","Intervention includes 3 sessions per week of combined strength and resistance exercise. Two of the sessions are supervised, while the third session is unsupervised-home-based.",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Ann-Katrin Grotle, PhD","PRINCIPAL_INVESTIGATOR",[29,33],{"name":26,"role":30,"phone":31,"phoneExt":11,"email":32},"CONTACT","+4790960580","ann-katrin.grotle@hvl.no",{"name":34,"role":30,"phone":35,"phoneExt":11,"email":36},"Brit Jorun Liseth, MSc","+4790013513","brit.jorun.fossan.liseth@hvl.no",[38],{"facility":5,"status":39,"city":40,"state":11,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Bergen","5063","Norway","NO",{"type":45,"coordinates":46},"Point",[47,48],5.32415,60.39299,{"lat":48,"lon":47},[51,52,53],{"name":26,"role":30,"phone":31,"phoneExt":11,"email":32},{"name":34,"role":30,"phone":35,"phoneExt":11,"email":36},{"name":26,"role":27,"phone":11,"phoneExt":11,"email":11},{"type":27,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Ann-Katrin Grotle","Associate professor","100636991","beetroot-juice-a-natural-aid-for-boosting-the-health-benefits-of-exercise-in-post-menopausal-women-100636991",false,"NCT07572877","Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?","BEETBOOST","Inclusion Criteria:\n\n* Self-reported biological female and postmenopausal (≥12 months of amenorrhea)\n* Aged 50-70 years\n* Body mass index (BMI) 25-39.9 kg\u002Fm²\n* No contraindications to exercise\n* Physically inactive (\\\u003C150 minutes\u002Fweek of moderate-intensity activity)\n* Able to walk on a treadmill and ambulate without limitations\n* Adequate proficiency in Norwegian to complete questionnaires\n* Willingness and ability to comply with the study schedule and visits\n\nExclusion Criteria:\n\n* Known allergy to nitrates or beetroot juice\n* Current smoker or use of nicotine\u002Ftobacco products\n* Resting blood pressure \\\u003C90\u002F60 mmHg\n* Hypertension greater than stage II (≥160\u002F100 mmHg, ESH criteria)\n* Use of prescription medications affecting heart rate (e.g., systemic β-adrenergic blockers) or nitrate availability (e.g., nitrates, proton pump inhibitors)\n* History of cardiovascular disease (e.g., myocardial infarction, stroke, ischemic heart disease, peripheral artery disease, valvular disease, or aortic aneurysm)\n* Symptoms suggestive of heart disease (e.g., chest pain or dyspnea)\n* Major metabolic disease (e.g., type 1 or type 2 diabetes) or thyroid disorders\n* Recent cancer diagnosis or treatment (within the past 5 years)\n* Significant orthopedic limitations or other contraindications to exercise\n* Diagnosed cognitive impairment\n* Planned travel or elective surgery that would interfere with adherence to the intervention\n* Psychological or social factors that may interfere with study participation\n* Residing beyond a reasonable distance from the study site (logistical constraints)","FEMALE","50 Years","70 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72],"NA","Menopause and ageing bring several changes to women's health, partly due to a decline in the hormone estrogen. This reduction affects multiple systems in the body, including muscles and bones, and also influences the production of nitric oxide, a molecule that plays a key role in regulating blood flow and blood pressure. An reduced ability to produce nitric oxide is associated with higher blood pressure and an increased risk of cardiovascular and metabolic diseases.\n\nMany women also experience lower levels of physical activity and changes in body composition during midlife, such as increased body fat and reduced muscle mass and strength, which may further decrease exercise capacity.\n\nThis PhD project investigates whether a simple, natural strategy, combining exercise with beetroot juice, can help postmenopausal women achieve greater benefits from exercise. Beetroot juice is naturally rich in nitrates, which the body can convert into nitric oxide, thereby enhancing blood flow. Exercise itself also stimulates nitric oxide production, and together these approaches may have additive or even synergistic effects.\n\nThe study examines whether consuming beetroot juice before exercise can enhance training adaptations and health outcomes in postmenopausal women. Key outcomes include cardiovascular function, body composition, musculoskeletal function, and aerobic capacity.\n\nSome evidence suggests that beetroot juice may amplify the body's response to exercise, which could be particularly beneficial for postmenopausal women, who often face greater barriers to physical activity. By exploring this combined approach, the project aims to evaluate a safe, non-pharmacological strategy to improve physical function and overall health in women after menopause.",[75],"Post-menopause",[77,78,79,80,81,82,83,84],"exercise","beetroot juice","strength training","endurance training","cardiometabolic health","muscleskeletal function","exercise performance","body composition","2026-05-11",{"date":87,"type":88},"2026-05-13","ACTUAL",{"date":90,"type":88},"2026-02-11",{"date":92,"type":69},"2033-01-01",{"name":5,"class":6},1]