[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587647":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":34,"centralContacts":38,"locations":18,"responsibleParty":44,"collaborators":18,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":18,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":18,"enrollmentInfo":57,"targetDuration":18,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":69,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":18},{"fullName":5,"class":6},"Peking University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group-B","EXPERIMENTAL","Participants will receive the AI-based HAPA and CEI behavioral intervention.",[13],"Behavioral: HAPA and CEI behavioral intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","Participants will receive non-personalized HIV prevention information, including free HIV testing and condom use, following the guidelines provided by the CDC and the operational standards of the community organizations, with weekly information push notifications.",null,{"label":20,"type":10,"description":21,"interventionNames":22},"Intervention group-A","Participants will receive HAPA-based behavioral intervention on the We-chat mini progarm.",[23],"Behavioral: HAPA-based intervention",[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":18},"BEHAVIORAL","HAPA and CEI behavioral intervention","The intervention group will receive a 3-month technology-facilitated PrEP intervention and tailored messages will be developed using BCTs based on theoretical guidance. PrEP teleconsultations will be delivered by certified healthcare professionals, including infectious disease specialists, CDC-affiliated prevention officers, and MSM community leaders. Participants will be stratified into peer cohorts through algorithm-driven grouping based on demographic characteristics. Six participants will form a peer group, and the economic incentive amount will be based on the group-level PrEP initiation rates (verified by physician prescriptions). The economic incentive will decrease progressively based on the average completion rate within the group and will be divided into three tiers: 22 USD (completion rate of 80-100%), 11 USD (completion rate of 50-79%), and 0 USD (completion rate \\\u003C50%).",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":18},"HAPA-based intervention","This group receives information pushes via a mini-program (3 messages per week) and two brief PrEP consultations; the first brief consultation is delivered jointly by community volunteers and a physician immediately after the baseline survey completion, based on a standardized consultation outline, and the second brief consultation is delivered jointly by community volunteers and a physician after the completion of the first monthly assessment (conducted within the mini-program), based on the standardized consultation outline and the results of that monthly assessment.",[20],[35],{"name":36,"affiliation":5,"role":37},"Wangnan Cao, Ph.D","PRINCIPAL_INVESTIGATOR",[39],{"name":40,"role":41,"phone":42,"phoneExt":18,"email":43},"Hao Lin","CONTACT","+86 18610528952","linhao@bjmu.edu.cn",{"type":37,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Wangnan Cao","Associate Professor","100587647","behavioral-intervention-for-prep-service-utilization-among-chinese-msm-a-hapa-and-cei-integrated-model-100587647",false,"NCT06931106","Behavioral Intervention for PrEP Service Utilization Among Chinese MSM: A HAPA and CEI Integrated Model","Behavioral Intervention to Enhance HIV Pre-Exposure Prophylaxis Service Utilization Among Men Who Have Sex With Men in China Based on Health Action Process Approach and Conditional Economic Incentives","Inclusion Criteria:\n\n* ≥18 years at enrollment;\n* Assigned male at birth with a history of ≥1 male-male sexual encounter (anal or oral intercourse);\n* HIV-negative confirmed by antibody testing at baseline;\n* No prior use of PrEP;\n* Expressed interest in PrEP intervention and commitment to complete scheduled follow-ups and data collection procedures;\n* Mentally competent to provide informed consent and participate in decision-making;\n* High HIV risk (meeting ≥1 of the following in the past 6 months): (1) Condomless anal\u002Fpenile-vaginal intercourse; (2)Shared needle use during illicit drug injection; (3) Sexual contact with HIV-positive partner(s); (4) Newly diagnosed STI; (5) Repeated use of PEP for HIV prevention; or (6) Self-identified as PrEP candidate through voluntary request.\n\nExclusion Criteria:\n\n* Confirmed HIV-positive status or unknown serostatus with refusal of HIV testing;\n* Clinically significant health conditions contraindicating PrEP use (e.g., creatinine clearance \\\u003C60 mL\u002Fmin, documented hypersensitivity to PrEP components);\n* Severe mental illness or neurological disorders impairing informed consent process.",true,"MALE","18 Years",{"count":58,"type":59},360,"ESTIMATED","INTERVENTIONAL",[62],"NA","The goal of this clinical trial is to evaluate the effectiveness of a novel, intelligent intervention platform in bridging the \"intention-behavior gap\" for pre-exposure prophylaxis (PrEP) uptake among men who have sex with men (MSM) in China, a population at high risk for HIV infection. The study aims to address the following main questions:\n\n* Can the intervention platform, guided by the Health Action Process Approach (HAPA) and Conditional Economic Incentive (CEI) dual-track theoretical framework, significantly increase PrEP initiation rates among MSM?\n* What are the key mechanisms and pathways underlying the transition from PrEP intention to actual usage behavior?\n\nResearchers will compare participants receiving the intelligent intervention platform (intervention group) with those receiving basic PrEP information (control group) to determine the platform's impact on PrEP initiation rates. Participants will:\n\n* Use a mobile health platform equipped with personalized HIV risk assessments, PrEP knowledge resources, action planning tools, peer support features, and economic incentives.\n* Complete baseline and follow-up surveys at 3 months and 6 months to assess PrEP initiation, adherence, and related behaviors.\n* Engage in peer group activities and receive tailored feedback based on their progress.\n\nThis study seeks to provide evidence for scalable and sustainable strategies to improve PrEP uptake and contribute to HIV prevention efforts in high-risk populations.",[65,66,67,68],"HIV","PrEP","MSM","Behavior Changes",[65,70,71,72,73],"pre-exposure prophylaxis","men who have sex with men","health action process approach","economic incentive","NOT_YET_RECRUITING","2025-05-30",{"date":77,"type":78},"2025-06-04","ACTUAL",{"date":80,"type":59},"2025-07",{"date":82,"type":59},"2026-08",{"name":5,"class":6}]