[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100638811":3},{"organization":4,"armGroups":7,"interventions":45,"overallOfficials":59,"centralContacts":64,"locations":44,"responsibleParty":73,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":44,"enrollmentInfo":89,"targetDuration":44,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":104,"whyStopped":44,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":44},{"fullName":5,"class":6},"Boston University","OTHER",[8,14,19,24,28,32,36,40],{"label":9,"type":10,"description":11,"interventionNames":12},"Behavioral Activation","EXPERIMENTAL","Participants in this arm will receive the behavioral activation intervention.",[13],"Behavioral: Behavioral Activation (BA)",{"label":15,"type":10,"description":16,"interventionNames":17},"Attendance Reinforcement","Participants in this arm will receive the Attendance Reinforcement intervention.",[18],"Behavioral: Attendance Reinforcement (AR)",{"label":20,"type":10,"description":21,"interventionNames":22},"Peer-Delivered Motivational Interviewing","Participants in this arm will receive the Peer-Delivered Motivational Interviewing Intervention.",[23],"Behavioral: Peer-Delivered Motivational Interviewing (PDMI)",{"label":25,"type":10,"description":26,"interventionNames":27},"Behavioral Activation + Attendance Reinforcement","Participants in this arm will receive the Behavioral Activation and Attendance Reinforcement interventions.",[13,18],{"label":29,"type":10,"description":30,"interventionNames":31},"Behavioral Activation + Peer-Delivered Motivational Interviewing","Participants in this arm will receive the Behavioral Activation and Peer-Delivered Motivational Interviewing interventions.",[13,23],{"label":33,"type":10,"description":34,"interventionNames":35},"Attendance Reinforcement + Peer-Delivered Motivational Interviewing","Participants in this arm will receive the Attendance Reinforcement and Peer-Delivered Motivational Interviewing interventions.",[18,23],{"label":37,"type":10,"description":38,"interventionNames":39},"Behavioral Activation + Attendance Reinforcement + Peer-Delivered Motivational Interviewing","Participants in this arm will receive the Behavioral Activation, Attendance Reinforcement, and Peer-Delivered Motivational Interviewing interventions.",[13,18,23],{"label":41,"type":42,"description":43,"interventionNames":44},"Treatment As Usual","NO_INTERVENTION","Participants randomized to this arm will receive usual care at their office based addiction treatment facility.",null,[46,51,55],{"type":47,"name":48,"description":49,"armGroupLabels":50,"otherNames":44},"BEHAVIORAL","Behavioral Activation (BA)","Trained study interventionists will deliver the manualized BA intervention aimed at increasing meaningful and enjoyable non-substance-related activities in early recovery. This intervention will include 12 individual sessions delivered to participants every other week for 6 months. The BA intervention will be delivered remotely by telephone or video visit to minimize treatment burden on patients.",[9,25,37,29],{"type":47,"name":52,"description":53,"armGroupLabels":54,"otherNames":44},"Attendance Reinforcement (AR)","A voucher incentive protocol will be implemented with increasing rewards based on clinical attendance at outpatient addiction treatment visits. The timing of clinical visits will be determined by site-specific usual care practices at both sites. Participants are expected to earn a range of payments for visit attendance according to their unique clinical schedule (which is dictated by their addiction medicine clinical team, not by research investigators).",[15,33,25,37],{"type":47,"name":56,"description":57,"armGroupLabels":58,"otherNames":44},"Peer-Delivered Motivational Interviewing (PDMI)","Trained study peer recovery coaches will deliver a multi-session intervention aimed at increasing treatment confidence for treatment continuation and providing social support during early recovery. The peer recovery coach will deliver brief MI (20-minute) individual sessions remotely every other week over the 6-month period (total 12 sessions). Peer interventionists will also be informed about local recovery resources to provide navigation support individually. PDMI will be delivered remotely by telephone or video visit.",[33,37,29,20],[60],{"name":61,"affiliation":62,"role":63},"Michael Stein, MD","BUSPH, Health Law, Policy & Management","PRINCIPAL_INVESTIGATOR",[65,69],{"name":61,"role":66,"phone":67,"phoneExt":44,"email":68},"CONTACT","(617) 638-5042","mdstein@bu.edu",{"name":70,"role":66,"phone":71,"phoneExt":44,"email":72},"Sally Bendiks, MPH","(617) 414-3802","Sally.Bendiks@bmc.org",{"type":74,"investigatorFullName":44,"investigatorTitle":44,"investigatorAffiliation":44,"oldNameTitle":44,"oldOrganization":44},"SPONSOR",[76],{"name":77,"class":78},"National Institute on Drug Abuse (NIDA)","NIH","100638811","behavioral-optimization-for-overcoming-suboptimal-treatment-retention-bup-booster-100638811",false,"NCT07607743","Behavioral Optimization for Overcoming Suboptimal Treatment Retention (BUP-BOOSTeR)","BUP-BOOSTeR: Behavioral Optimization for Overcoming Suboptimal Treatment Retention","BUP-BOOSTeR","Inclusion Criteria:\n\n* 18 years of age or older\n* Meet DSM V criteria for opioid use disorder during the past year\n* Be a patient in Office Based Addiction Treatment who has initiated buprenorphine in the last 30 days AND has had no use of prescribed buprenorphine in the 7 days before the current treatment episode AND has not received long-acting injectable buprenorphine in the 6 weeks before the current treatment episodes OR Be a person within the first 30 days of release from a carceral setting who is taking any formulation of buprenorphine for their OUD and who is within their first 30 days of intake at OBAT.\n* Be willing to provide informed consent, be randomized, and complete study materials\n* Be able to speak and read English sufficiently to complete study intervention and procedures\n* Be willing to provide the study access to their electronic medical records\n* Have no plans to change Office Based Addiction Treatment clinics during the study\n\nExclusion Criteria:\n\n-Be receiving hospice or other end of life medical care","ALL","18 Years",{"count":90,"type":91},240,"ESTIMATED","INTERVENTIONAL",[94],"NA","Buprenorphine, a medication for opioid use disorder (MOUD), is associated with decreased opioid overdose and all-cause mortality. Treatment outcomes improve if patients remain on MOUD for at least six months, a period recommended by expert guidelines, although most studies report retention on MOUD of 50-65% at 3-6 months. Psychosocial interventions have the potential to improve MOUD treatment retention particularly when applied in combination in efficient delivery systems.\n\nThe objective of this study is to develop an effective and efficient multicomponent intervention to increase buprenorphine retention at 6 months through an optimization trial.",[97],"Opioid Use Disorder",[99,100,101,102,103],"Behavioral activation","Attendance reinforcement","Peer motivational interviewing","Multiphase Optimization STrategy (MOST)","Buprenorphine","NOT_YET_RECRUITING","2026-05-24",{"date":107,"type":108},"2026-05-28","ACTUAL",{"date":110,"type":91},"2026-09",{"date":112,"type":91},"2029-12",{"name":5,"class":6}]