[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622789":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":58,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":25,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":90,"whyStopped":25,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Salamanca","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Progressive Muscle Relaxation","ACTIVE_COMPARATOR","Participants in this arm will receive one weekly session of progressive muscle relaxation over a 10-week period. Each session will last approximately 45 minutes and will include diaphragmatic breathing, Jacobson's progressive muscle relaxation technique, controlled breathing exercises, and a brief cooldown period. Sessions will be supervised by a trained physiotherapist.",[13],"Behavioral: Progressive Muscle Relaxation",{"label":15,"type":16,"description":17,"interventionNames":18},"Strength Training plus Progressive Muscle Relaxation","EXPERIMENTAL","Participants in this arm will receive a combined intervention consisting of one weekly session of progressive muscle relaxation and one weekly session of functional strength training over a 10-week period. Strength training sessions will focus on upper limb, lower limb, and core muscle groups using progressive resistance. Each session will last approximately 45 minutes and will be supervised by a trained physiotherapist.",[13,19],"Behavioral: Functional Strength Training",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Progressive muscle relaxation will be delivered in weekly supervised sessions over a 10-week period. Each session will last approximately 45 minutes and will include diaphragmatic breathing, systematic muscle contraction and relaxation following Jacobson's technique, controlled breathing exercises, and a brief cooldown period. The intervention will be administered by a trained physiotherapist in a group setting.",[9,15],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Functional Strength Training","Functional strength training will be delivered in weekly supervised sessions over a 10-week period. Sessions will last approximately 45 minutes and will focus on improving upper limb, lower limb, and core muscle strength using progressive resistance exercises. Training intensity will be gradually increased according to participant tolerance and performance. All sessions will be supervised by a trained physiotherapist.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Andrea Calleja Caballero, Principal Investigator","CONTACT","+34 616957689","andreacallejac@usal.es",[37],{"facility":38,"status":25,"city":39,"state":25,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Universidad de Salamanca","Salamanca","37007","Spain","ES",{"type":44,"coordinates":45},"Point",[46,47],-5.66388,40.96882,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":52,"phoneExt":25,"email":53},"Fátima Perez-Robledo","+34 619 885 479","fatima_pr@usal.es",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Andrea Calleja Caballero","Physical therapist",[59,62],{"name":60,"class":61},"Colegio Profesional de Fisioterapeutas de Castilla y León","UNKNOWN",{"name":63,"class":61},"CRE Alzheimer del Imserso","100622789","benefits-of-strength-training-in-informal-caregivers-of-patients-with-alzheimers-disease-100622789",false,"NCT07388186","Benefits of Strength Training in Informal Caregivers of Patients With Alzheimer's Disease","Effectiveness of a Combined Strength Training and Progressive Muscle Relaxation Program in Reducing Frailty in Informal Caregivers of People With Alzheimer's Disease: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Informal caregivers of a person with Alzheimer's disease\n* Providing regular care for at least 10 hours per week\n* Ability to attend intervention sessions\n* Ability to understand and follow instructions\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Acute illness or medical conditions contraindicating participation in strength exercise\n* Participation in structured exercise programs that may interfere with study outcomes\n* Severe or uncontrolled psychiatric disorders\n* Physical limitations preventing completion of functional assessments",true,"ALL","18 Years",{"count":75,"type":76},62,"ESTIMATED","INTERVENTIONAL",[79],"NA","Informal caregivers of people with Alzheimer's disease experience high physical and psychological burden, increasing their risk of frailty, anxiety, and caregiver burnout. This randomized controlled trial aims to evaluate the effectiveness of a combined strength training and progressive muscle relaxation program compared with progressive muscle relaxation alone. The intervention will last 10 weeks, with assessments conducted at baseline, post-intervention, and at a 3-month follow-up. Primary outcomes include frailty, anxiety, and caregiver burden.",[82,83,84],"Frailty","Caregiver Burden","Anxiety",[82,86,87,84,88,89],"Strength","Caregiver","Burden","Alzheimer disease","NOT_YET_RECRUITING","2026-01-30",{"date":93,"type":94},"2026-02-04","ACTUAL",{"date":96,"type":76},"2026-03",{"date":98,"type":76},"2026-09",{"name":5,"class":6},1]