[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100309797":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":32,"collaborators":7,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":41,"eligibilityCriteria":42,"healthyVolunteers":43,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":7,"studyType":50,"phases":7,"briefSummary":51,"conditions":52,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Charite University, Berlin, Germany","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Florian Herse, PhD","CONTACT","+49 30 450 540 434","florian.herse@charite.de",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"Experimental and Clinical Research Center (ECRC)","RECRUITING","Berlin","13125","Germany","DE",{"type":23,"coordinates":24},"Point",[25,26],13.41053,52.52437,{"lat":26,"lon":25},[29,30],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"name":10,"role":31,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"type":31,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Florian Herse","PhD","100309797","berlin-brandenburg-pregnancy-cohort-100309797",false,"NCT03313024","Berlin-Brandenburg Pregnancy Cohort","Characterization of Immune Cell-trophoblast-interaction in Pregnancy Disorders","BBPC","Inclusion Criteria:\n\n* healthy pregnant women after giving informed consent\n* pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes\n\nExclusion Criteria:\n\n* infections\n* alcohol and drug abuse\n* manifest and chronic diseases",true,"FEMALE","18 Years","45 Years",{"count":48,"type":49},1580,"ESTIMATED","OBSERVATIONAL","This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.",[53,54,55],"Preeclampsia","Pregnancy Complications","Diabetes Mellitus in Pregnancy","2018-08-13",{"date":58,"type":59},"2018-08-14","ACTUAL",{"date":61,"type":59},"2017-09-26",{"date":63,"type":49},"2027-10",{"name":5,"class":6},1]