[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603866":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":26,"responsibleParty":42,"collaborators":26,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":26,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":71,"whyStopped":26,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":26},{"fullName":5,"class":6},"Ondokuz Mayıs University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BIA-Guided Fluid Therapy","EXPERIMENTAL","Patients in this group will receive postoperative fluid therapy guided by bioelectrical impedance analysis (BIA) using the Body Composition Monitor (BCM) device. Daily fluid decisions will be based on measurements such as Extracellular water (ECW)\u002F Total body water (TBW) and phase angle.",[13],"Device: Bioelectrical Impedance Analysis (BCM)",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional Fluid Therapy","ACTIVE_COMPARATOR","Patients in this group will receive conventional fluid management based on routine clinical parameters, including vital signs, urine output, physical examination, and laboratory values. No bioelectrical impedance analysis will be performed in this group.",[19],"Procedure: Conventional Fluid Management",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Bioelectrical Impedance Analysis (BCM)","The Body Composition Monitor (BCM) device will be used to perform daily bioelectrical impedance measurements to guide fluid resuscitation in critically ill patients after major surgery. Measurements include extracellular water, intracellular water, total body water, and phase angle. The results will be used to tailor fluid therapy.",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"PROCEDURE","Conventional Fluid Management","Patients in this group will receive fluid therapy based on standard clinical parameters including blood pressure, heart rate, urine output, laboratory values, and physical examination. No bioelectrical impedance measurement will be performed.",[15],[33],{"name":34,"affiliation":5,"role":35},"Fatma Ülger","STUDY_DIRECTOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Kübra Tabur","CONTACT","+905396067171","ddoktortas@gmail.com",{"type":43,"investigatorFullName":44,"investigatorTitle":5,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Fatma ULGER","100603866","bia-guided-vs-conventional-fluid-resuscitation-in-icu-patients-100603866",false,"NCT07142083","BIA-Guided vs. Conventional Fluid Resuscitation in ICU Patients","Comparison of the Effects of Bioelectrical Impedance Analysis-Guided Versus Conventional Fluid Resuscitation Strategies on 28-Day Mortality in Intensive Care Unit Patients After Major Surgery","BIA-FLUID","Inclusion Criteria:\n\n* Undergoing major surgery under general anesthesia(Major surgery defined as: vascular clamping or organ ischemia, intraoperative blood loss \\>1000 mL, need for \\>10 mcg\u002Fmin norepinephrine infusion, surgery duration \\>4 hours, or requirement for perioperative blood transfusion)\n* Admission to the intensive care unit (CU) after surgery\n* Informed consent obtained\n\nExclusion Criteria:\n\n* Refusal to participate or failure to provide informed consent\n* Undergoing laparoscopic or emergency surgery\n* Severe major organ dysfunction:Acute kidney injury stage 2 or 3 (KDIGO 2012) • Acute or chronic liver failure (ALT \\>3x or Child A-C cirrhosis\n* Conditions preventing accurate BIA measurement: • Limb amputation • Metallic cardiac or joint prostheses • Pacemakers or intracardiac stents\n* Body mass index \\>35 kg\u002Fm or \\\u003C 18 kg\u002Fm\n* Contraindications to lactated Ringer's solution (e.g. hypercalcemia, increased intracranial pressure)","ALL","18 Years","60 Years",{"count":57,"type":58},80,"ESTIMATED","INTERVENTIONAL",[61],"NA","In this study aimed to compare bioelectrical impedance analysis (BIA)-guided fluid resuscitation with conventional fluid management strategies in patients admitted to the intensive care unit (ICU) following major surgery. The primary objective is to evaluate whether BIA-guided fluid therapy reduces 28-day mortality by optimizing fluid balance and preventing volume-related complications. Secondary outcomes include cumulative fluid balance, ICU and hospital length of stay, duration of mechanical ventilation, and need for vasopressor or inotropic support. This study is expected to provide evidence for the clinical utility and applicability of BIA in guiding postoperative fluid therapy in critically ill patients.",[64,65],"Fluid and Electrolyte Imbalance","Anesthesia",[67,68,69,70],"Bioelectrical impedance analysis","Intensive Care","Fluid Resuscitation","Postoperative Fluid Management","NOT_YET_RECRUITING","2025-09-01",{"date":74,"type":75},"2025-09-08","ACTUAL",{"date":77,"type":58},"2025-09-15",{"date":79,"type":58},"2026-12-01",{"name":5,"class":6}]