[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596458":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":47,"collaborators":49,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"TecSalud Investigación Clínica","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Lumbar Spinal Stenosis Cases",null,"Patients diagnosed with lumbar spinal stenosis who exhibit persistent neurological deficits and pain despite receiving at least three months of conservative treatment. All participants have elected to undergo ULBLD using endoscopic uniportal technique. They are being prospectively followed to evaluate improvements in neurological function and reductions in pain-related disability, as well as to document perioperative outcomes including surgical time, blood loss, hospital stay, and complications.",[13],"Procedure: Unilateral Laminotomy with Bilateral Lumbar Decompression (ULBLD)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Unilateral Laminotomy with Bilateral Lumbar Decompression (ULBLD)","Unilateral laminotomy with bilateral lumbar decompression (ULBLD) using endoscopic uniportal technique",[9],[21],{"name":22,"affiliation":5,"role":23},"Mario Benvenutti Regato, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","(+52) 81 8888 0675","mbenreg@tec.mx",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Hospital Zambrano Hellion, TecSalud","RECRUITING","San Pedro Garza García","Nuevo León","66278","Mexico","MX",{"type":39,"coordinates":40},"Point",[41,42],-100.40651,25.6604,{"lat":42,"lon":41},[45,46],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[50,52,54,57],{"name":51,"class":6},"Tecnologico de Monterrey",{"name":53,"class":6},"Centro Medico Nacional Siglo XXI IMSS",{"name":55,"class":56},"Hospital Ángeles Tijuana","UNKNOWN",{"name":58,"class":56},"Hospital Zambrano Hellion TecSalud, Mexico","100596458","bilateral-lumbar-decompression-via-uniportal-endoscopic-laminotomy-in-patients-with-lumbar-spinal-stenosis-multicentric-case-series-100596458",false,"NCT07045714","Bilateral Lumbar Decompression Via Uniportal Endoscopic Laminotomy in Patients With Lumbar Spinal Stenosis: Multicentric Case Series","MELD-1","Inclusion Criteria:\n\n* Provision of informed consent to participate in the study.\n* Age ≥18 years and \\\u003C75 years.\n* Patients with lumbar spinal stenosis grade I-III according to the Lee scale.\n* Radicular or myelopathic symptoms.\n* Having undergone complete conservative management, including physical therapy and analgesia, for at least 3 months.\n* Patients who have opted for ULBLD using endoscopic uniportal technique for lumbar spinal stenosis.\n\nExclusion Criteria:\n\n* Inability to read or write.\n* Prior lumbar surgeries at the levels to be treated.\n* Infectious symptoms or concomitant rheumatologic diseases.\n* Criteria of lumbar vertebral instability.\n* Congenital spinal malformations.\n* Disc herniation at the same lumbar level to be operated on.\n* Medullary hyperintensity on T2-weighted magnetic resonance imaging in the levels to be treated.","ALL","18 Years","74 Years",{"count":70,"type":71},78,"ESTIMATED","OBSERVATIONAL","Lumbar spinal stenosis is a condition that can cause pain, sensory disturbances, and motor deficits due to the compression of neural structures in the lumbar spine. While conservative treatments such as physical therapy and pain management can help some patients, others with persistent neurological deficits may require surgical intervention. Traditional surgical approaches, including open laminectomy, have proven effective but carry risks such as extensive muscle damage, considerable blood loss, postoperative spinal instability, and prolonged recovery times.\n\nThis study evaluates a minimally invasive surgical approach called unilateral laminotomy with bilateral lumbar decompression (ULBLD) using endoscopic uniportal technique as an alternative to traditional methods for patients with lumbar spinal stenosis. The main objective is to assess changes in neurological deficits and disability in patients with lumbar spinal stenosis following this procedure. The study will also document hospitalization duration, surgical time, blood loss, and the incidence of postoperative complications.\n\nThis multicenter, prospective case series will recruit 78 patients from three medical centers in Mexico. Participants must have symptomatic lumbar spinal stenosis that persists despite at least three months of conservative treatment. Eligible patients will undergo ULBLD using endoscopic uniportal technique, a method that allows precise nerve decompression through a small incision, minimizing damage to surrounding tissues. Standardized clinical assessment tools, including the Japanese Orthopaedic Association (JOA) scale for lumbar disease, Oswestry Disability Index (ODI), and Visual Analog Scale (VAS) for pain, will be used to evaluate outcomes at multiple time points over 12 months.\n\nBy comparing patients' preoperative and postoperative evaluations, the study aims to determine whether ULBLD using endoscopic uniportal technique effectively improves neurological function and reduces disability while maintaining a favorable safety profile. Findings from this study could lead to a more precise understanding of the impact of ULBLD on disability, pain, and health-related quality of life for patients with lumbar spinal stenosis.",[75],"Spinal Stenosis Lumbar",[77,78,79,80],"Lumbar Spinal Stenosis","Minimally Invasive Surgical Procedures","Endoscopic Spine Surgery","Spinal Degenerative Disease","2026-03-03",{"date":83,"type":84},"2026-03-04","ACTUAL",{"date":86,"type":84},"2026-02-25",{"date":88,"type":71},"2027-07",{"name":5,"class":6},1]