[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533698":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":37,"locations":11,"responsibleParty":42,"collaborators":11,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":11,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":11,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":68,"whyStopped":11,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":11},{"fullName":5,"class":6},"Sichuan University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Billroth II with Braun Reconstruction","EXPERIMENTAL",null,[13,14],"Procedure: Billroth II reconstruction","Procedure: Braun Anastomosis",{"label":16,"type":17,"description":11,"interventionNames":18},"Billroth II Reconstruction","ACTIVE_COMPARATOR",[13],[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Billroth II reconstruction","Billroth II reconstruction, in which a loop of jejunum is mobilized and anastomosed to the gastric remnant",[16,9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Braun Anastomosis","This is an additional surgical connection (anastomosis) created between two parts of the small intestine, specifically between the afferent (incoming) and efferent (outgoing) limbs of the jejunum near the gastrojejunostomy (the new connection between the stomach and small intestine created during a Billroth II procedure).",[9],[30,34],{"name":31,"affiliation":32,"role":33},"Bo Zhang, MD","Gastric Cancer Center, Department of General Surgery, West China Hospital, Sichuan University","STUDY_CHAIR",{"name":35,"affiliation":32,"role":36},"Zhaolun Cai, MD, PhD","PRINCIPAL_INVESTIGATOR",[38],{"name":35,"role":39,"phone":40,"phoneExt":11,"email":41},"CONTACT","+86-028-85423610","caizhaolun@foxmail.com",{"type":36,"investigatorFullName":31,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Professor","100533698","billroth-ii-with-braun-anastomosis-after-radical-distal-gastrectomy-for-gastric-cancer-100533698",false,"NCT06229197","Billroth II With Braun Anastomosis After Radical Distal Gastrectomy for Gastric Cancer","Billroth II With Braun Anastomosis Versus Billroth II Anastomosis After Radical Distal Gastrectomy With D2 Lymphadenectomy for Gastric Cancer: a Randomized Controlled Trial","Inclusion criteria\n\nTo be enrolled, participants must be phase I-III patients with initial treatment of radical distal gastrectomy and satisfying the following inclusion criteria:\n\n1. Histologically proven stage I-III gastric cancer, evaluated as radically resectable\n2. No synchronous or metachronous cancers\n3. Patients have signed informed consent forms\n4. Age 18-80 years old\n5. No malfunction of cardio-pulmonary, liver, and kidney, ECOG score 0-1\n6. No emergency surgery needed\n\nExclusion criteria\n\nPatients will be excluded according to the following criteria:\n\n1. Pregnant or lactating women\n2. Distant metastasis to the liver, lung, bone, supraclavicular lymph nodes, pelvic, or ovarian species and peritoneal dissemination\n3. Ascites or cachexia\n4. Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, poorly controlled hypertension or diabetes\n5. Participation in other clinical trials 4 weeks before the enrollment of this trial or still participating in other trials\n6. Mental illness\n7. Surgical history whose influence has not been eliminated\n8. History of another gastric or esophageal malignancy, including stromal tumor, sarcoma, lymphoma, and carcinoid\n9. Active infection with a fever of over 38°C\n10. Poor compliance\n11. Not suitable for this trial because of other clinical or laboratory conditions determined by the researchers","ALL","18 Years","80 Years",{"count":55,"type":56},176,"ESTIMATED","INTERVENTIONAL",[59],"NA","The primary aim of this trial is to rigorously evaluate the comparative benefits and potential risks associated with Billroth II reconstruction with Braun anastomosis versus Billroth II reconstruction alone following distal gastrectomy with D2 lymphadenectomy in patients diagnosed with gastric cancer. This assessment focuses on delineating the therapeutic efficacy, safety profile, and overall clinical outcomes of these two surgical approaches in treating this condition.",[62,63,64,65],"Gastric Cancer","Surgery","Anastomosis","Gastrostomy",[62,65,67,26],"Billroth II","NOT_YET_RECRUITING","2024-01-18",{"date":71,"type":72},"2024-01-29","ACTUAL",{"date":74,"type":56},"2024-02-01",{"date":76,"type":56},"2027-12-31",{"name":5,"class":6}]