[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626564":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":65,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"group A Bimanual Training Group","EXPERIMENTAL","Participants in this group will receive structured bimanual training designed to improve coordination, reduce spasticity, and enhance functional use of both upper limbs. The intervention will be delivered three sessions per week for 8 weeks, with each session lasting 60 minutes. Activities will include repetitive, goal-directed bilateral tasks such as buttoning shirts, folding clothes, opening containers, building with blocks, and bimanual play activities. Each session will be divided into three 20-minute activity blocks with 5-minute rest intervals to prevent fatigue. All sessions will be supervised by a certified pediatric physiotherapist trained in neurorehabilitation. In addition, participants will receive standardized baseline physiotherapy education at the start of the study.",[13],"Behavioral: Bimanual Training",{"label":15,"type":16,"description":17,"interventionNames":18},"group B Unilateral Task-Specific Training Group","ACTIVE_COMPARATOR","Participants in this group will receive unilateral task-specific training focused on intensive use of the affected upper limb to promote neuroplasticity and functional recovery. The intervention will be delivered three sessions per week for 8 weeks, with each session lasting 60 minutes. Activities will include grasp-and-release exercises, reaching, stacking, drawing, flipping cards, and manipulation of objects using the affected hand. The unaffected hand may be mildly restrained when necessary to encourage active use of the affected limb without causing frustration. Sessions will be structured into three 20-minute blocks with 5-minute rest intervals. Standardized baseline physiotherapy education will also be provided at the beginning of the study.",[19],"Behavioral: Unilateral Task-Specific Training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Bimanual Training","Bimanual training is a structured, task-oriented upper limb rehabilitation program designed to promote coordinated use of both hands during functional, goal-directed activities. The intervention emphasizes active involvement of the affected upper limb within bilateral tasks rather than isolating it. Therapy will be delivered three sessions per week for 8 weeks, with each session lasting 60 minutes.\n\nEach session will consist of three 20-minute activity blocks with 5-minute rest intervals to reduce fatigue. Activities will include age-appropriate, real-life bilateral tasks such as buttoning shirts, folding clothes, opening containers, building with blocks, drawing with both hands, catching and throwing balls, and interactive bimanual play tasks. Task complexity will be progressively increased based on the child's tolerance and performance.\n\nUnlike unilateral training, this approach focuses on improving interlimb coordination, motor planning, and functional integration of both upper limb",[9],null,{"type":22,"name":28,"description":28,"armGroupLabels":29,"otherNames":26},"Unilateral Task-Specific Training",[15],[31],{"name":32,"affiliation":33,"role":34},"Muhammad Hasnain Soomro, MSPTN","The University of Lahore, Lahore","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","03158463003","drhasnainsoomro@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Montiha Azeem, MSPTN","03479717317","muntahaazeem9@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"University of Lahore Teaching Hospital, Lahore","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":54,"coordinates":55},"Point",[56,57],74.35071,31.558,{"lat":57,"lon":56},[60,63,64],{"name":61,"role":37,"phone":38,"phoneExt":26,"email":62},"Muhammad Hasnain Soomro, MSPT N","drhusnainsoomro@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},{"name":32,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Montiha Azeem","principal investigator","100626564","bimanual-training-versus-unilateral-task-specific-training-in-children-with-spastic-hemiplegic-cerebral-palsy-100626564",false,"NCT07437274","Bimanual Training Versus Unilateral Task Specific Training in Children With Spastic Hemiplegic Cerebral Palsy","BUST-CP","Inclusion Criteria:\n\nBoth male and female Children diagnosed with spastic hemiplegic cerebral palsy (confirmed by a pediatric neurologist or rehabilitation specialist).\n\nAge range: 5 to 12 years (suitable for both bimanual and unilateral task-specific training).\n\nGross Motor Function Classification System (GMFCS) levels I to III (ambulatory with or without limitations).\n\nModified Ashworth Scale score between 1 and 3 in the upper limb muscles (indicating mild to moderate spasticity).\n\nMinimum cognitive ability to follow simple instructions, verified using screening tools (e.g., MMSE adapted for children).\n\nAbility to sit unsupported for at least 30 seconds (to ensure safe participation in therapy).\n\nExclusion Criteria:\n\nChildren with mixed types of cerebral palsy (e.g., spastic quadriplegia, dyskinetic, or ataxic types).\n\nRecent orthopedic surgery or botulinum toxin injections in the affected upper limb within the past 6 months.\n\nSevere visual, auditory, or sensory deficits that could interfere with therapy participation or assessment accuracy.\n\nUncontrolled epilepsy or other neurological conditions that could compromise safety during therapy.\n\nFixed joint contractures or severe deformities in the upper limbs that limit passive range of motion Children with behavioral or psychological disorders (e.g., severe ADHD, autism spectrum disorder) that impair attention or participation","ALL","5 Years","15 Years",{"count":80,"type":81},46,"ESTIMATED","INTERVENTIONAL",[84],"NA","Cerebral palsy is one of the most common childhood neurological disorders and often results in weakness, poor coordination, and stiffness (spasticity) in one side of the body in children with spastic hemiplegic cerebral palsy. These difficulties can significantly affect a child's ability to perform daily activities such as dressing, eating, playing, and school-related tasks.\n\nUpper limb rehabilitation plays a crucial role in improving independence and quality of life in these children. Two commonly used rehabilitation approaches are bimanual training, which focuses on using both hands together during functional tasks, and unilateral task-specific training, which focuses intensively on improving the affected hand through repetitive, goal-directed activities.\n\nAlthough both approaches are widely practiced in pediatric neurorehabilitation, there is limited direct comparison of their effectiveness in reducing spasticity and improving functional independence among children with spastic hemiplegic cerebral palsy, particularly in the local population of Pakistan.\n\nThis randomized controlled trial aims to compare the effectiveness of bimanual training versus unilateral task-specific training in children aged 5-12 years diagnosed with spastic hemiplegic cerebral palsy. A total of 46 participants will be randomly assigned to one of two intervention groups. Both groups will receive therapy three times per week for eight weeks.\n\nSpasticity will be measured using the Modified Ashworth Scale (MAS), and functional independence will be assessed using the Pediatric Evaluation of Disability Inventory (PEDI). Assessments will be conducted before and after the intervention period.\n\nThe results of this study may help clinicians, caregivers, and rehabilitation centers determine which therapy approach is more effective in improving upper limb function and independence in children with spastic hemiplegic cerebral palsy. Participation in this study is voluntary, and children may withdraw at any time without affecting their standard care.",[87],"Spastic Cerebral Palsy (sCP)",[23,28,89,90],"Pediatric Neurorehabilitation","Functional Independence","2026-03-05",{"date":93,"type":94},"2026-03-09","ACTUAL",{"date":96,"type":81},"2026-03-01",{"date":98,"type":81},"2026-05-02",{"name":67,"class":6},1]