[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626579":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":61,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":25,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":91,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Miami","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Binaural Beats (BB)","EXPERIMENTAL","Participants assigned to this arm will listen to a 30-minute binaural beats audio session at a comfortable volume through standardized over-ear headphones while in the post-anesthesia care unit (PACU). The audio will use a primary target frequency of 10 Hz (alpha range), created using soft sine-wave carriers in the 200-600 Hz range that generate a 10 Hz interaural difference (e.g., 400 Hz left ear \u002F 410 Hz right ear). Volume will be set at a comfortable conversational level (\\~55-65 dBA) and may be adjusted by the participant. The session will begin within 15 minutes of PACU arrival. Participants may stop the audio at any time.",[13],"Other: Binaural Beats Audio Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Music of Choice (MOC)","ACTIVE_COMPARATOR","Participants in this arm will receive usual postoperative care in the post-anesthesia care unit (PACU) and may listen to music of their choice using standardized headphones. They will select their preferred music and listen for 30 minutes at a comfortable volume (\\~55-65 dBA), which they may adjust as needed. No binaural beat frequencies will be used. Music listening is optional and may be stopped at any time.",[19],"Other: Music of Choice",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Binaural Beats Audio Intervention","30-minute binaural beats audio session targeting 400 and 410 hertz (Hz) alpha 400 hertz (Hz) in one ear 410 hertz (Hz) in other ear frequency delivered through standardized headphones in the PACU.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Music of Choice","Usual postoperative care in addition to patient-selected music using standardized headphones",[15],[31],{"name":32,"affiliation":5,"role":33},"Victor H Hernandez, MD, MSc","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Andrew R Moya, MD","CONTACT","1786-856-6463","arm577@miami.edu, doc.a.moya1@gmail.com",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Univeristy of Miami Health System","RECRUITING","Miami","Florida","33132","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-80.19366,25.77427,{"lat":53,"lon":52},[56,59],{"name":36,"role":37,"phone":57,"phoneExt":25,"email":58},"786-856-6463","arm577@miami.edu",{"name":60,"role":33,"phone":25,"phoneExt":25,"email":25},"Victor H Hernandez, MD",{"type":33,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Victor Hugo Hernandez","Chief of Joint Replacement","100626579","binaural-beats-for-postoperative-pain-and-anxiety-reduction-100626579",false,"NCT07437469","Binaural Beats for Postoperative Pain and Anxiety Reduction","Binaural Beats vs Music of Choice for Early Postoperative Pain After Ambulatory Total Knee and Total Hip Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* American Society of Anesthesiologists Physical Status Classification System (ASA) 1-3\n* Spinal anesthesia\n* Patients receiving nerve-block in Post-Anesthesia Care Unit (PACU)\n* Primary total hip or total knee arthroplasty\n\nExclusion Criteria:\n\n* Moderate-severe hearing impairment or use of hearing aids\n* History of significant tinnitus, active delirium, chronic high-dose opioid therapy (\\>60 MME\u002Fday baseline)\n* Major psychiatric pathology\n* General anesthesia","ALL","18 Years","99 Years",{"count":75,"type":76},50,"ESTIMATED","INTERVENTIONAL",[79],"NA","To deliver a 30-minute binaural beats audio intervention in PACU and collect pain and anxiety outcomes immediately following surgery, and 4 hours following surgery completion in adults undergoing ambulatory total knee arthroplasty and total hip arthroplasty (TKA and THA).",[82,83,84,85,86,87,88,89,90],"TKA","THA","Anxiety","Binaural Beats","Music Exposure","Total Hip Arthroplasty (THA)","Total Knee Arthroplasty","Total Knee Replacement","Total Hip Replacement",[83,82,92,93,84,94,85,86],"Total hip arthroplasty","Total knee arthroplasty","Pain","2026-04-29",{"date":97,"type":98},"2026-04-30","ACTUAL",{"date":100,"type":98},"2026-03-09",{"date":102,"type":76},"2026-08-30",{"name":5,"class":6},1]