[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584327":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":13,"responsibleParty":34,"collaborators":7,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":7,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":7,"enrollmentInfo":47,"targetDuration":7,"studyType":50,"phases":7,"briefSummary":51,"conditions":52,"keywords":7,"overallStatus":16,"whyStopped":7,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"PROCEDURE","Carotid endarterectomy","Carotid endarterectomy, plaque histological analysis and miRNA expression",[14],{"facility":15,"status":16,"city":17,"state":18,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"Fondazione Policlinico Universitario A. Gemelli IRCCS","RECRUITING","Roma","RM","00167","Italy","IT",{"type":23,"coordinates":24},"Point",[25,26],11.10642,44.99364,{"lat":26,"lon":25},[29],{"name":30,"role":31,"phone":32,"phoneExt":7,"email":33},"Giovanni Tinelli","CONTACT","0039 0630157205","giovanni.tinelli@policlinicogemelli.it",{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","TINELLI GIOVANNI","Associate Professor of Vascular Surgery","100584327","biomarkers-and-unstable-carotid-plaque-100584327",false,"NCT06887894","Biomarkers and Unstable Carotid Plaque","EVALUATION OF NEW BIOMARKERS IN THE IDENTIFICATION OF UNSTABLE CAROTID PLAQUE","Inclusion Criteria:\n\n* Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy.\n* Age\\>18 years\n\nExclusion Criteria:\n\n* Presence of significant internal carotid artery stenosis referred to carotid artery stenting","ALL","18 Years",{"count":48,"type":49},200,"ESTIMATED","OBSERVATIONAL","This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.",[53],"Carotid Artery Diseases","2025-03-15",{"date":56,"type":57},"2025-03-20","ACTUAL",{"date":59,"type":57},"2019-09-01",{"date":61,"type":49},"2027-12-31",{"name":5,"class":6},1]