[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580349":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":19,"centralContacts":23,"locations":31,"responsibleParty":49,"collaborators":51,"id":55,"slug":7,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":7,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":67,"studyType":68,"phases":7,"briefSummary":69,"conditions":70,"keywords":7,"overallStatus":33,"whyStopped":7,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Rush University Medical Center","OTHER",null,[9,13,16],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","MRI","MRI during hospitalization and at 12 months post sICH",{"type":10,"name":14,"description":15,"armGroupLabels":7,"otherNames":7},"Blood Draw","Will occur during hospitalization and at 3, 6 and 12 months post sICH",{"type":10,"name":17,"description":18,"armGroupLabels":7,"otherNames":7},"Cognitive Test","Cognitive testing will occur during hospitalization and at 3, 6 and 12 months post sICH",[20],{"name":21,"affiliation":5,"role":22},"Rajeev Garg, MD","PRINCIPAL_INVESTIGATOR",[24,29],{"name":25,"role":26,"phone":27,"phoneExt":7,"email":28},"Amanda Sremac, BS","CONTACT","312-942-0593","Amanda_C_Sremac@rush.edu",{"name":21,"role":26,"phone":7,"phoneExt":7,"email":30},"Rajeev_Garg@rush.edu",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Chicago","Illinois","60614","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-87.65005,41.85003,{"lat":43,"lon":42},[46,47,48],{"name":21,"role":26,"phone":7,"phoneExt":7,"email":30},{"name":25,"role":26,"phone":27,"phoneExt":7,"email":28},{"name":21,"role":22,"phone":7,"phoneExt":7,"email":7},{"type":50,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[52],{"name":53,"class":54},"National Institute of Neurological Disorders and Stroke (NINDS)","NIH","100580349",false,"NCT06836141","Biomarkers for Cognitive Decline in Intracerebral Hemorrhage","Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia (VCID)","Inclusion Criteria:\n\n* Primary Intracerebral Hemorrhage\n* Age ≥ 18 and \\\u003C 80 years\n\nExclusion Criteria:\n\n* ICH score \\> 2\n* Pre-existing dementia\n* Prior history of stroke\n* Neurosurgical evacuation of hematoma","ALL","18 Years","80 Years",{"count":65,"type":66},118,"ESTIMATED","12 Months","OBSERVATIONAL","The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are\n\n* if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline\n* if SBIs in sICH are associated with certain findings on brain imaging\n* if SBIs in sICH are associated with higher inflammation measured by certain blood tests\n\nParticipants will undergo\n\n* cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH\n* Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH\n* blood draws during hospitalization and at 3, 6 and 12 months after the sICH",[71],"Primary Intracerebral Hemorrhage","2025-08-06",{"date":74,"type":75},"2025-08-08","ACTUAL",{"date":77,"type":75},"2025-08-02",{"date":79,"type":66},"2029-08-01",{"name":5,"class":6},1]