[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100448259":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":52,"centralContacts":60,"locations":65,"responsibleParty":135,"collaborators":137,"id":140,"slug":141,"hasResults":142,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":146,"eligibilityCriteria":147,"healthyVolunteers":142,"sex":148,"minAge":149,"maxAge":10,"enrollmentInfo":150,"targetDuration":10,"studyType":153,"phases":10,"briefSummary":154,"conditions":155,"keywords":157,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":167},{"fullName":5,"class":6},"Region Skane","OTHER",[8,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"VAP",null,"Enrolled participants that fully meet the criteria of VAP.",[13,14,15,16,17],"Diagnostic Test: Heparin-binding protein","Diagnostic Test: 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VAP.",[23,19,9],[39],"IL-26",{"type":28,"name":41,"description":42,"armGroupLabels":43,"otherNames":10},"Microbiome","Evaluation of the specificity and sensitivity of the lung microbiome as prognostic biomarker for VAP.",[23,19,9],{"type":28,"name":45,"description":46,"armGroupLabels":47,"otherNames":10},"Bacterial transcriptome","Evaluation of the specificity and sensitivity of the bacterial transcriptome as prognostic biomarker for treatment failure of VAP.",[9],{"type":28,"name":49,"description":50,"armGroupLabels":51,"otherNames":10},"Proteome","Evaluation of the specificity and sensitivity of the proteome in mini-BAL as biomarker for VAP.",[23,19,9],[53,57],{"name":54,"affiliation":55,"role":56},"Magnus Paulsson, PhD MD","Skane University Hospital","PRINCIPAL_INVESTIGATOR",{"name":58,"affiliation":55,"role":59},"Fredrik Sjövall, PhD 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1000","pedro.povoa@nms.unl.pt",{"facility":100,"status":68,"city":101,"state":10,"zip":10,"country":102,"countryCode":103,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Skåne University Hospital, Dept. of Infectious diseases","Lund","Sweden","SE",{"type":74,"coordinates":105},[106,107],13.19321,55.70584,{"lat":107,"lon":106},[110],{"name":111,"role":62,"phone":112,"phoneExt":10,"email":64},"Magnus Paulsson, MD PhD","+4646175431",{"facility":114,"status":68,"city":115,"state":10,"zip":10,"country":102,"countryCode":103,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Skåne university Hospital, ICU","Malmö",{"type":74,"coordinates":117},[118,119],13.00073,55.60587,{"lat":119,"lon":118},[122],{"name":58,"role":62,"phone":10,"phoneExt":10,"email":10},{"facility":124,"status":125,"city":126,"state":10,"zip":10,"country":102,"countryCode":103,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Karolinska University Hospital, ICU","NOT_YET_RECRUITING","Solna",{"type":74,"coordinates":128},[129,130],18.00086,59.36004,{"lat":130,"lon":129},[133],{"name":134,"role":62,"phone":10,"phoneExt":10,"email":10},"Johan Petersson, PhD MD",{"type":136,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[138],{"name":139,"class":6},"Lund University","100448259","biomarkers-for-ventilator-associated-pneumonia-100448259",false,"NCT05117125","Biomarkers for Ventilator-associated Pneumonia","Biomarkers for Prediction of and Diagnosis of Ventilator-associated Pneumonia","VAPmarkers","Inclusion Criteria:\n\n* Admission to an intensive care unit\n* Intubation within last 24 hours\n* Anticipated mechanical ventilation of at least 48 hours\n\nExclusion Criteria:\n\n* FiO2 above 70% or PEEP above 15\n* Severe coagulopathy (spontaneous PK(INR) \\>1.8 or thrombocytes \\\u003C50). Prophylaxis treatment dose of LMWH or factor Xa inhibitors\u002FNOAC is not an exclusion criteria. If higher doses of these substances are administered, the responsible clinician should be consulted before sample collection.\n* Ongoing infection of the lungs at admission to the ICU.\n* Severely elevated or instable intracranial pressure.","ALL","18 Years",{"count":151,"type":152},1000,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to evaluate different peptide biomarkers, variations in the microbiome and patterns in the bacterial transcriptome as prognostic or diagnostic biomarkers of VAP.",[156],"Pneumonia, Ventilator-Associated",[9],"2026-06-25",{"date":160,"type":161},"2026-06-26","ACTUAL",{"date":163,"type":161},"2021-10-15",{"date":165,"type":152},"2028-12-31",{"name":5,"class":6},5]