[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570841":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":28,"responsibleParty":44,"collaborators":46,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":10,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Maimónides Biomedical Research Institute of Córdoba","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"AN",null,"Patients with Anorexia Nervosa diagnosed according to the DSM-V criteria.",{"label":13,"type":10,"description":14,"interventionNames":10},"AN-R","Patients recovered from Anorexia Nervosa",{"label":16,"type":10,"description":17,"interventionNames":10},"CON","Healthy subjects of the same age and gender as all other groups",[19],{"name":20,"affiliation":21,"role":22},"Marta Camacho-Cardenosa, pHd","Maimonides Biomedical Research Institute of Córdoba","PRINCIPAL_INVESTIGATOR",[24],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+34 957213814","marta.camacho@imibic.org",[29],{"facility":30,"status":10,"city":31,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Hospital Universitario Reina Sofía, Edificio IMIBIC, Avd. Menedez Pdial, s\u002Fn","Córdoba","14004","Spain","ES",{"type":36,"coordinates":37},"Point",[38,39],-4.77275,37.89155,{"lat":39,"lon":38},[42],{"name":43,"role":25,"phone":26,"phoneExt":10,"email":27},"Marta Camacho-Cardenosa",{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[47],{"name":48,"class":49},"Hospital Universitario Reina Sofia de Cordoba","OTHER_GOV","100570841","biomarkers-in-ev-associated-with-marrow-adiposity-in-anorexia-100570841",false,"NCT06712485","Biomarkers in EV Associated With Marrow Adiposity in Anorexia","Identification of Biomarkers in Extracellular Vesicles Associated With Marrow Adiposity and Bone Deterioration Caused by Nutritional Deficiencies","VE_BMAT_AN","Inclusion Criteria:\n\nFor AN group:\n\n* Diagnosis of active AN according to DSM-5 criteria\n* BMI of less than 17kg\u002Fm2\n* Present amenorrhoea in the 3 months prior to the start of the study.\n\nFor AN-R group:\n\n* Achieved weight gain of more than 85%.\n* Normal menstruation in the last 3 months.\n\nFor Control group:\n\n* Population of the same age and gender as the AN and AN-R groups.\n* If pubertal population, presenting a chronological age of ± 2 years.\n* Normal menstruation\n* Normal BMI (\\>18.5 kg\u002Fm2)\n* No presence of previous dietary transtrons.\n\nExclusion Criteria:\n\n* Not receiving oestrogens, contraceptives or glucocorticoids in the 3 months prior to the start of the study.\n* Not to suffer from chronic diseases, such as diabetes, pathologies affecting the bone system or thyroid function.\n* Do not take calcium or vitamin supplements.",true,"ALL",{"count":61,"type":62},30,"ESTIMATED","OBSERVATIONAL","The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa. The main question it aims to answer is:\n\nCan this medullary adiposity be associated with the bone deterioration observed in this population?\n\nParticipants will be assessed for body composition and a blood sample will be taken by non-invasive techniques.",[66,67],"Anorexia Nervosa Restricting Type","Anorexia Nervosa (DSM-IV Revised Criteria)",[69,70,71,72,73],"Extracellular Vesicles","Bone Deterioration","Biomarkers","Bone Marrow Adipose Tissue","Nutritional Deficiencies","NOT_YET_RECRUITING","2025-05-05",{"date":77,"type":78},"2025-05-07","ACTUAL",{"date":80,"type":62},"2025-05-15",{"date":82,"type":62},"2026-07-31",{"name":5,"class":6},1]