[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606983":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":39,"locations":47,"responsibleParty":66,"collaborators":10,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":10,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":91,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Endometriosis",null,"Moderate\u002Fsevere endometriosis",[13,14,15],"Diagnostic Test: Endometrial fluid","Diagnostic Test: Endometrial biopsy","Diagnostic Test: Follicular fluid",{"label":17,"type":10,"description":18,"interventionNames":19},"Controls","Healthy women undergoing oocyte pick up",[13,14],[21,26,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"DIAGNOSTIC_TEST","Endometrial fluid","Endometrial fluid collection in the day of OPU",[17,9],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"Endometrial biopsy","Endometrial biopsy on the OPU day, Pipelle",[17,9],{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Follicular fluid","Follicular fluid sampling on the OPU day",[9],[35],{"name":36,"affiliation":37,"role":38},"Kenny Rodriguez-Wallberg, Professor","Onk\u002FPat Karolinska Institute","PRINCIPAL_INVESTIGATOR",[40,45],{"name":41,"role":42,"phone":43,"phoneExt":10,"email":44},"Anastasia Drakou, MSc, PhD student","CONTACT","+46735500118","anastasiadrakou1989@gmail.com",{"name":36,"role":42,"phone":10,"phoneExt":10,"email":46},"kenny.rodriguez-wallberg@ki.se",[48],{"facility":49,"status":10,"city":50,"state":10,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Karolinska Institute and Karolinska University Hospital Huddinge","Stockholm","14433","Sweden","SE",{"type":55,"coordinates":56},"Point",[57,58],18.06871,59.32938,{"lat":58,"lon":57},[61,63,64],{"name":41,"role":42,"phone":62,"phoneExt":10,"email":44},"0735500118",{"name":10,"role":42,"phone":10,"phoneExt":10,"email":44},{"name":41,"role":65,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":67,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100606983","biomarkers-in-the-endometrial-fluid-tissue-and-follicular-fluid-of-moderatesevere-endometriosis-patients-100606983",false,"NCT07182643","Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate\u002FSevere Endometriosis Patients","An Exploratory Study of Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate\u002FSevere Endometriosis Patients: a Prospective Study","Inclusion Criteria:\n\n* Age 18-40 years old\n* Diagnosed with moderate\u002Fsevere endometriosis by ultrasound or laparoscopy (patient group)\n* Regular menstrual cycles 28-35 days\n* Speak English or Swedish and agree to participate in the study\n\nExclusion Criteria:\n\n* Pregnancy or lactation in the last 3 months\n* Uterine anomalies\n* Pelvic inflammatory disease, endometritis, STD\n* Gynaecological cancers or other malignancies in the patient's history\n* Smoking (more than 10 cigarettes per day) or alcohol abuse\n* Immunosuppressing medicines\n* Major abdominal or pelvic surgery in the last 3 months\n* A specific genetic disease that is diagnosed before PGT in women undergoing treatment",true,"FEMALE","18 Years","40 Years",{"count":80,"type":81},90,"ESTIMATED","OBSERVATIONAL","This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation. This research has the potential to uncover diagnostic indicators of impaired pre-receptive endometrium, examine pathophysiological pathways, and identify future targets for therapeutic intervention. Ultimately, the findings may contribute to more personalized fertility treatments, offering new hope for women struggling with endometriosis-related infertility.",[9],[86,87,88,89,90],"endometriosis","biomarkers","implantation","infertility","fertility","NOT_YET_RECRUITING","2025-09-16",{"date":94,"type":95},"2025-09-19","ACTUAL",{"date":97,"type":81},"2025-10-01",{"date":99,"type":81},"2027-12-31",{"name":5,"class":6},1]