[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600132":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":22,"locations":10,"responsibleParty":28,"collaborators":10,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":37,"eligibilityCriteria":38,"healthyVolunteers":39,"sex":40,"minAge":41,"maxAge":10,"enrollmentInfo":42,"targetDuration":45,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":10,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":10},{"fullName":5,"class":6},"Zhejiang Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with cerebral small vessel disease",null,"Patients with at least one following imaging finding: white matter hyperintensities (Fazekas \\>or=1), lacune, cerebral microbleeds, recent small subcortical infarcts, or enlarged perivascular spaces (Grade 2 or more).",[13],"Other: No intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients without cerebral small vessel disease","Patients without any following imaging finding: white matter hyperintensities (Fazekas \\>or=1), lacune, cerebral microbleeds, recent small subcortical infarcts, or enlarged perivascular spaces (Grade 2 or more).",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"No intervention",[9,15],[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Junjun Wang","CONTACT","8613777848063","wjj005@163.com",{"type":29,"investigatorFullName":24,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Senior Research Scientist","100600132","biomarkers-risk-assessment-imaging-and-neurodegeneration-in-cerebral-small-vessel-disease-brain-csvd-100600132",false,"NCT07093515","Biomarkers, Risk Assessment, Imaging, and Neurodegeneration in Cerebral Small Vessel Disease (BRAIN-CSVD)","A Cohort Study of Biomarkers, Risk Assessment, Imaging, and Neurodegeneration in Patients With Cerebral Small Vessel Disease","BRAIN-CSVD","Inclusion Criteria:\n\n* Age \\>= 18 years old;\n* Cerebral small vessel disease on MR imaging.\n\nExclusion Criteria:\n\n* Cerebral infarction (except lacunar infarcts), cerebral hemorrhage, brain tumors, epilepsy, severe traumatic brain injury, or prior brain surgery;\n* Secondary white matter hyperintensities due to inflammatory, toxic causes and so on;\n* Contraindications to MRI.",true,"ALL","18 Years",{"count":43,"type":44},500,"ESTIMATED","5 Years","OBSERVATIONAL","The BRAIN-CSVD study is a single-center prospective cohort study focusing on cerebral small vessel disease (CSVD).Patients enrolled in this research will undergo assessments for vascular risk factors, cognitive and other neurological functions, neuroimaging, and biomarkers. The study aims to explore imaging and biomarker predictors of CSVD progression, and the pathophysiological mechanisms of CSVD.",[49],"Cerebral Small Vessel Disease","NOT_YET_RECRUITING","2025-07-29",{"date":53,"type":54},"2025-07-30","ACTUAL",{"date":56,"type":44},"2025-10",{"date":58,"type":44},"2032-12-30",{"name":5,"class":6}]