[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100536129":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":45,"centralContacts":49,"locations":58,"responsibleParty":76,"collaborators":28,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":28,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":28,"overallStatus":61,"whyStopped":28,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Universitaire Ziekenhuizen KU Leuven","OTHER",[8,18],{"label":9,"type":10,"description":11,"interventionNames":12},"PTTD patients (PTTD I, II and III)","EXPERIMENTAL","75 patients with PTTD (25 patients in Stage I, 25 patients in Stage II, 25 patients in Stage III)",[13,14,15,16,17],"Diagnostic Test: Radiography","Diagnostic Test: Ultrasound","Diagnostic Test: MRI","Diagnostic Test: CT-scan","Diagnostic Test: Gait analysis",{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy control group","25 healthy volunteers",[13,16,17],[23,29,33,37,41],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"DIAGNOSTIC_TEST","Radiography","X-rays of the ankle; anterior-posterior, lateral, Mortise view and hindfoot alignment view. Standard weight bearing x-rays of the foot; anterior-posterior, lateral and oblique view.",[19,9],null,{"type":24,"name":30,"description":31,"armGroupLabels":32,"otherNames":28},"Ultrasound","Ultrasound of the posterior tibial tendon to see if there is an irritation, elongation or rupture.",[9],{"type":24,"name":34,"description":35,"armGroupLabels":36,"otherNames":28},"MRI","MRI when ultrasound is not conclusive to identify an irritation, elongation or rupture of the posterior tibial tendon.",[9],{"type":24,"name":38,"description":39,"armGroupLabels":40,"otherNames":28},"CT-scan","CT-scan to identify arthritis of the tibial-talar, subtalar and\u002For Chopart joints.",[19,9],{"type":24,"name":42,"description":43,"armGroupLabels":44,"otherNames":28},"Gait analysis","This lab is equipped with a 10-meter walkway surrounded by a passive optoelectronic motion analysis system consisting of 10 cameras to track the motion of markers. In the middle of the walkway, a force plate is integrated, with a pressure plate placed on top.",[19,9],[46],{"name":47,"affiliation":5,"role":48},"Sander Wuite","PRINCIPAL_INVESTIGATOR",[50,54],{"name":47,"role":51,"phone":52,"phoneExt":28,"email":53},"CONTACT","+32 16 33 83 29","sander.wuite@uzleuven.be",{"name":55,"role":51,"phone":56,"phoneExt":28,"email":57},"Kevin Deschamps","+32 16 33 88 27","kevin.deschamps@uzleuven.be",[59],{"facility":60,"status":61,"city":62,"state":63,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"UZ Leuven","RECRUITING","Leuven","Vlaams-Brabant","3000","Belgium","BE",{"type":68,"coordinates":69},"Point",[70,71],4.70093,50.87959,{"lat":71,"lon":70},[74,75],{"name":47,"role":51,"phone":52,"phoneExt":28,"email":53},{"name":55,"role":51,"phone":56,"phoneExt":28,"email":57},{"type":77,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR","100536129","biomechanical-and-morphological-characterization-of-pttd-100536129",false,"NCT06260813","Biomechanical and Morphological Characterization of PTTD","Biomechanical and Morphological Characterization of the Foot in Patients With Posterior Tibial Tendon Dysfunction.","PTTD","Inclusion criteria:\n\n* Patient groups:\n\n  * Posterior tibial tendon dysfunction (all clinical stages)\n  * Age 18-675 year\n  * ICF obtained\n* Control group:\n\n  * No pain complaints\n  * No pes plano valgus, PTTD or pes cavo varus or other foot and ankle pathology\n  * Age 18-75 year\n  * ICF obtained\n\nExclusion criteria patient and control groups:\n\n* Being younger than 18 years\n* Inability to walk without mobility aids\n* Inability to walk \\\u003C 100 meter\n* Difference in leg length \\> 3cm\n* Subjects with BMI\\>30 kg\u002Fm², due to less accurate gait analysis by absence of anatomical landmarks\n* Subjects unable to perform a gait analysis\n* Any medical condition possibly affecting normal gait.\n* Pregnancy: at the start or during the study",true,"ALL","18 Years","75 Years",{"count":91,"type":92},100,"ESTIMATED","INTERVENTIONAL",[95],"NA","Posterior tibial tendon dysfunction (PTTD) is a progressive condition of the tendon of the tibialis posterior muscle with symptoms of tendinopathy or even rupture. Functionally, it is associated with the inability to lock the mid foot and thus manifests itself as a main contributor to adult acquired flatfoot deformity.\n\nConcerning treatment, clinical decision making is currently based on a classification integrating various parameters as pain, flexibility of the foot joints, the condition of the posterior tibial tendon assessed through ultrasound imaging and radiographic assessment of arthritic changes. Surprisingly, this classification does not consider any morphologic characteristics (the shape of a bone or joint) or functional, biomechanical characteristics of the foot and ankle, i.e. based on kinematics (e.g. range of motion) and\u002For kinetics (center of pressure, angular velocity, moment, power absorption and power generation of a joint).\n\nDetailed biomechanical characteristics of the foot and ankle can be reliably collected by instrumented gait analysis wherein a 3D camera system is combined with a force plate and plantar pressure platform. Kinematic studies in the field of PTTD typically considered the foot as a structure consisting of three segments: hind foot, forefoot and hallux. Consequently, the mid foot segment (the Chopart and Lisfranc joints) has been neglected, although it is this segment that is particularly affected in PTTD patients.\n\nThe aim of this research is to overcome the limitations of the current classification system and treatment of PTTD patients, by complementing the current standard-of-care clinical assessment with better insight in the pathologic changes that occur in PTTD patients.",[98],"Posterior Tibial Tendon Dysfunction","2025-04-10",{"date":101,"type":102},"2025-04-15","ACTUAL",{"date":104,"type":102},"2022-08-22",{"date":106,"type":92},"2028-08-01",{"name":5,"class":6},1]