[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639093":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":22,"locations":31,"responsibleParty":73,"collaborators":75,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":10,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":108,"whyStopped":10,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":118},{"fullName":5,"class":6},"Uniformed Services University of the Health Sciences","FED",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"High exposure (experimental)",null,"Special Operations Forces personnel with higher occupational blast overpressure exposure as measured by blast sensor(s)",{"label":13,"type":10,"description":14,"interventionNames":10},"Low\u002FNo exposure (control)","Special Operations Forces personnel with lower occupational blast overpressure exposure as measured by blast sensor(s)",[16,19],{"name":17,"affiliation":5,"role":18},"Vincent B Ho, MD","STUDY_CHAIR",{"name":20,"affiliation":5,"role":21},"Tony T Yuan, PhD","PRINCIPAL_INVESTIGATOR",[23,27],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},"CONTACT","214-808-8971","tony.yuan@usuhs.edu",{"name":28,"role":24,"phone":29,"phoneExt":10,"email":30},"Carrie W Hoppes, PhD","571-212-4660","carrie.hoppes.ctr@usuhs.edu",[32,47,61],{"facility":33,"status":10,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Walter Reed National Military Medical Center","Bethesda","Maryland","20889","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-77.10026,38.98067,{"lat":43,"lon":42},[46],{"name":20,"role":24,"phone":25,"phoneExt":10,"email":26},{"facility":48,"status":10,"city":48,"state":49,"zip":50,"country":37,"countryCode":38,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"Fort Bragg","North Carolina","28310",{"type":40,"coordinates":52},[53,54],-79.00603,35.139,{"lat":54,"lon":53},[57],{"name":58,"role":24,"phone":59,"phoneExt":10,"email":60},"Rodney Saunders, MSN","740-398-1391","rodney.saunders.ctr@usuhs.edu",{"facility":62,"status":10,"city":63,"state":64,"zip":65,"country":37,"countryCode":38,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Wilford Hall Ambulatory Surgical Center","San Antonio","Texas","78236",{"type":40,"coordinates":67},[68,69],-98.49363,29.42412,{"lat":69,"lon":68},[72],{"name":28,"role":24,"phone":29,"phoneExt":10,"email":30},{"type":74,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[76,79],{"name":77,"class":78},"The Geneva Foundation","OTHER",{"name":80,"class":81},"MIT Lincoln Laboratory","UNKNOWN","100639093","blast-overpressure-longitudinal-study-100639093",false,"NCT07606651","Blast Overpressure Longitudinal Study","Blast Overpressure Longitudinal Exposure Study (BLES)","BLES","Inclusion Criteria:\n\n* Active duty\n* U.S. SOF personnel\n* 18-50 years old\n\nExclusion Criteria:\n\n* Subjects will be excluded only if their participation will significantly interfere with validity of data collection or safety during the study (e.g., they have conditions that might result in harm or injury during research procedures).\n* Example: pregnancy (balance considerations)\n* Example: being unable to undergo MRI testing (i.e., they have non-MRI compatible devices, imbedded metal fragments such as shrapnel, and\u002For severe claustrophobia; these MRI contraindications will be screened using an MRI Safety Questionnaire)",true,"ALL","18 Years","50 Years",{"count":95,"type":96},250,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the impact of low-level blast exposure in U.S. Special Operations Forces personnel. The main questions it aims to answer are:\n\nWhat advanced brain imaging changes are related to clinical presentation after low-level blast exposure? What are the relationships between low-level blast exposure and common groups of symptoms after concussion?\n\nParticipants will:\n\n* Undergo advanced brain imaging\n* Answer questionnaires\n* Complete clinical tests\n* Provide blood, urine, and saliva samples\n* Wear blast sensors",[100],"Low-level Blast Exposure",[102,103,104,105,106,107],"traumatic brain injury","concussion","magnetic resonance imaging","blast overpressure","low-level blast exposure","repeated blast exposure","NOT_YET_RECRUITING","2026-05-18",{"date":111,"type":112},"2026-05-26","ACTUAL",{"date":114,"type":96},"2026-05",{"date":116,"type":96},"2030-08",{"name":5,"class":6},3]