[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613271":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":36,"locations":10,"responsibleParty":45,"collaborators":47,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":82,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":10},{"fullName":5,"class":6},"Cardiovascular and Interventional Radiological Society of Europe","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Adult patients with bleeding grade II-III haemorrhoids",null,"Adult patients with bleeding grade II-III haemorrhoids planned to be treated with Haemorrhoid artery embolization (HAE) using embolization coils",[13],"Procedure: Haemorrhoid artery embolizsation (HAE)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Haemorrhoid artery embolizsation (HAE)","Haemorrhoid artery embolization (HAE) is a minimally invasive procedure used to treat symptomatic haemorrhoids by reducing their blood supply. Under imaging guidance, typically fluoroscopy, a catheter is inserted through a small puncture in the groin or wrist and guided into the arteries that supply the haemorrhoidal tissue, known as the superior rectal arteries.\n\nOnce the target vessels are identified, embolization coils-tiny metal coils designed to block blood flow-are placed inside these arteries. The coils create a controlled blockage, decreasing blood flow to the haemorrhoids, which helps shrink the swollen tissue and reduce bleeding.\n\nHAE is usually performed as an day-case procedure under local anaesthesia with mild sedation, and tends to result in less pain, quicker recovery, and lower complication rates compared to surgical approaches.",[9],[21],"Embolization Coils",[23,27,30,33],{"name":24,"affiliation":25,"role":26},"Clare Bent, Dr","Royal Bournemouth Hospital, University Hospitals Dorset NHS Foundation Trust","STUDY_CHAIR",{"name":28,"affiliation":29,"role":26},"Christoph A. Binkert, Prof. Dr. med.","Medical Radiological Institute",{"name":31,"affiliation":32,"role":26},"Roberto Iezzi, Prof.","Fondazione Policlinico Agostino Gemelli, IRCCS Catholic University",{"name":34,"affiliation":35,"role":26},"Vincent Vidal, Prof.","Marseille University Hospital Timone",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Claire Poulet, PhD","CONTACT","+41 79 385 16 78","bright@cirse.org",{"name":43,"role":39,"phone":44,"phoneExt":10,"email":41},"Dhwani S. Korde, PhD","+4367762942469",{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[48,51],{"name":49,"class":50},"Medtronic","INDUSTRY",{"name":52,"class":50},"Cook Group Incorporated","100613271","bleeding-reduction-in-grade-ii-iii-haemorrhoids-through-embolization-treatment-100613271",false,"NCT07264413","Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment","BRIGHT","Inclusion Criteria:\n\n1. Adult patients presenting bleeding Grade II-III haemorrhoids with French bleeding score ≥3 planned to be treated with HAE using embolization coils;\n2. Patients competent and willing to give written informed consent.\n\nExclusion Criteria:\n\n1. Minors and other vulnerable populations who may not be able to give informed consent freely or for whom participation is not essential to the study (incapacitated and unconscious individuals, persons deprived of liberty, pregnant and breastfeeding women, etc.);\n2. Patients receiving HAE using a combination of coils and particles, particles only, or any other embolic agents;\n3. Patients who have had previous surgical haemorrhoidectomy at any time or other treatments for haemorrhoids within 1 year before the planned HAE;\n4. Patients with known perianal sepsis, inflammatory bowel disease, peri-anal fistula, colorectal malignancy or pre-existing sphincter injury resulting in incontinence;\n5. Patients with an immunodeficiency;\n6. Known severe atheromatous disease with occlusion of target vessels preventing embolization;\n7. Absolute contraindication to contrast media;\n8. ECOG performance status \\> 2;\n9. Life expectancy \\\u003C 12 months;\n10. Patients with unstable angina;\n11. Patients currently taking nicorandil.","ALL","18 Years",{"count":63,"type":64},250,"ESTIMATED","OBSERVATIONAL","BRIGHT is a Europe-wide study that will follow up to 250 adults with bleeding symptoms from haemmorhoids (Grade II-III categories). It aims to understand how well a minimally invasive procedure called haemorrhoid artery embolization (HAE) works in everyday clinical practice, which is a technique that blocks the blood vessels feeding the haemorrhoids. As this technique does not require major surgery, HAE offers several benefits such as less trauma, quicker recovery, and the use of only local anaesthesia.",[68,69],"Hemorrhoid","Hemorrhoid Bleeding",[71,72,73,74,75,76,77,78,79,80,81],"Haemorrhoids","Grade II-III haemorrhoids","Symptomatic haemorrhoids","Hemorrhoidal bleeding","Haemorrhoidal disease","Haemorrhoid artery embolization","HAE","Artery embolization","Transarterial embolization","Minimally invasive","Embolization coils","NOT_YET_RECRUITING","2026-07-01",{"date":85,"type":86},"2026-07-02","ACTUAL",{"date":88,"type":64},"2026-08",{"date":90,"type":64},"2030-12",{"name":5,"class":6}]