[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100405041":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":40,"responsibleParty":95,"collaborators":99,"id":102,"slug":103,"hasResults":104,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":104,"sex":110,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":24,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":24,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Physical Therapy with Sham BFRT","ACTIVE_COMPARATOR","Participants will undergo 8 weeks of sham blood flow restriction training with cuff inflated to less than 10% occlusion.",[13],"Device: Sham Blood Flow Restriction Training",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard Physical Therapy with BFRT","Participants will undergo 8 weeks of blood flow restriction training with cuff inflated to 60% occlusion.",[18],"Device: Blood Flow Restriction Training",[20,25],{"type":21,"name":22,"description":16,"armGroupLabels":23,"otherNames":24},"DEVICE","Blood Flow Restriction Training",[15],null,{"type":21,"name":26,"description":11,"armGroupLabels":27,"otherNames":24},"Sham Blood Flow Restriction Training",[9],[29],{"name":30,"affiliation":5,"role":31},"Caitlin Conley, PhD","STUDY_DIRECTOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","8592571939","caitlin.conley2@uky.edu",{"name":38,"role":34,"phone":24,"phoneExt":24,"email":39},"Natalie Corey","natalie.corey@uky.edu",[41,58,69,84],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"UK Healthcare at Turfland","RECRUITING","Lexington","Kentucky","40504","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-84.47772,37.98869,{"lat":53,"lon":52},[56],{"name":30,"role":34,"phone":57,"phoneExt":24,"email":36},"859-257-1939",{"facility":59,"status":43,"city":44,"state":45,"zip":60,"country":47,"countryCode":48,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"University of Kentucky Biomotion Laboratory","40536",{"type":50,"coordinates":62},[52,53],{"lat":53,"lon":52},[65],{"name":66,"role":34,"phone":67,"phoneExt":24,"email":68},"Brian Noehren, PhD, PT","8592180581","b.noehren@uky.edu",{"facility":70,"status":43,"city":71,"state":72,"zip":73,"country":47,"countryCode":48,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Center for Sports Performance and Research","Foxborough","Massachusetts","02035",{"type":50,"coordinates":75},[76,77],-71.24783,42.06538,{"lat":77,"lon":76},[80],{"name":81,"role":34,"phone":82,"phoneExt":24,"email":83},"Molly Zgoda","508-216-1145","mzgoda@mgb.org",{"facility":85,"status":43,"city":71,"state":72,"zip":73,"country":47,"countryCode":48,"cosmosGeoPoint":86,"geoPoint":88,"contacts":89},"Foxboro Sports Medicine Clinic",{"type":50,"coordinates":87},[76,77],{"lat":77,"lon":76},[90,94],{"name":91,"role":34,"phone":92,"phoneExt":24,"email":93},"Cale Jacobs, PhD","508-216-1145.","cjacobs@bwh.harvard.edu",{"name":81,"role":34,"phone":92,"phoneExt":24,"email":83},{"type":96,"investigatorFullName":97,"investigatorTitle":98,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Caitlin Conley","Assistant Professor",[100],{"name":101,"class":6},"The Cleveland Clinic","100405041","blood-flow-restriction-training-after-patellar-instability-100405041",false,"NCT04554212","Blood Flow Restriction Training After Patellar INStability","Blood Flow Restriction Training After Patellar INStability (BRAINS Trial)","BRAINS","Inclusion Criteria:\n\n* Diagnosis of traumatic patellar instability (either primary or recurrent) determined by an American Board of Family Medicine certified physician with a Certificate of Added Qualifications in Sports Medicine or licensed Physical Therapist utilizing clinical examination, radiographic imaging, and patients' reports of instability\n* Age 14 to 40 years\n* Skeletally mature with closed growth plates visualized by radiograph\n* A score of 80 or more on the Sports Activity Scale, which corresponds to participating in \"running, twisting, turning (tennis, racquetball, handball, ice hockey, field hockey, skiing, wrestling)\" at least 1-3 times per week\n* Desire to resume pre-injury activity level\n\nExclusion Criteria:\n\n* Concomitant osteochondral lesion requiring surgical fixation\n* Radiographic evidence of osteoarthritis (\\\u003C Kellgren-Lawrence Grade 2)\n* Previous ipsilateral or contralateral knee surgery\n* Most recent instability event more than 3 months before enrollment\n* History of any inflammatory disorder\n* BMI \\> 35 kg\u002Fm2\n* Diabetes or uncontrolled hypertension\n* Varicose veins or a history of personal or immediate family history (parental or sibling) of deep vein thrombosis\n* Pre-existing conditions or previous surgeries that effect the ability to walk\n* Planned trips or vacations that will result in the inability to attend 4 consecutive physical therapy sessions","ALL","14 Years","40 Years",{"count":114,"type":115},78,"ESTIMATED","INTERVENTIONAL",[118],"NA","This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.",[121,122,123,124],"Patellar Dislocation","Knee Injuries","Leg Injury","Wounds and Injuries","2025-07-02",{"date":127,"type":128},"2025-07-03","ACTUAL",{"date":130,"type":128},"2020-09-09",{"date":132,"type":115},"2026-06-30",{"name":97,"class":6},4]