[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591897":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":26,"responsibleParty":36,"collaborators":26,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":26,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":26,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":26,"overallStatus":59,"whyStopped":26,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":26},{"fullName":5,"class":6},"West China Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BFRT Group","EXPERIMENTAL","\"Blood flow restriction training with 20% 1RM loading, pneumatic cuff pressure 80-100mmHg (arms)",[13],"Device: Blood Flow Restriction Training (BFRT)",{"label":15,"type":16,"description":17,"interventionNames":18},"CRT Group","ACTIVE_COMPARATOR","Conventional resistance training at 65-75% 1RM intensity using weights\u002Felastic bands, matched frequency\u002Fduration",[19],"Other: Conventional Resistance Training (CRT)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Blood Flow Restriction Training (BFRT)","Standard progressive resistance exercise at 65-75% 1RM intensity using weights\u002Felastic bands",[9],null,{"type":6,"name":28,"description":24,"armGroupLabels":29,"otherNames":26},"Conventional Resistance Training (CRT)",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"yu liang","CONTACT","+86 13982250862","1536569213@qq.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Yuxiang Liang","Physiotherapist-in-Charge","100591897","blood-flow-restriction-training-for-age-related-sarcopenia-100591897",false,"NCT06986395","Blood Flow Restriction Training for Age-Related Sarcopenia","The Efficacy of Blood Flow Restriction Training in Elderly Patients With Sarcopenia.","Inclusion Criteria:\n\n* Hospitalized patients aged ≥65 years\n* Diagnosed with sarcopenia per EWGSOP2019 criteria\n* Acute medical conditions stabilized for ≥4 weeks (e.g., resolved infections, controlled heart failure)\n\nExclusion Criteria:\n\n* Severe disability (Barthel Index ≤40)\n* Significant cognitive impairment (MMSE ≤18) or major psychiatric disorders (DSM-5 criteria)\n* Contraindications to blood flow restriction training:\n\n  * History\u002Fpredisposition to deep vein thrombosis\n  * Coagulopathy (INR \\>1.5, platelets \\\u003C100×10⁹\u002FL)\n  * Symptomatic varicose veins (CEAP class C4-C6)\n  * Uncontrolled hypertension (BP \\>160\u002F100 mmHg)\n  * Chronic lymphedema (ISL stage II-III)\n  * Peripheral artery disease (ABI ≤0.7)\n  * Active systemic infection (CRP \\>10 mg\u002FL)\n  * Malignancy (except non-melanoma skin cancer)\n  * Severe renal impairment (eGFR \\\u003C30 mL\u002Fmin\u002F1.73m²)\n  * Acute coronary syndrome within 3 months","ALL","65 Years","100 Years",{"count":51,"type":52},40,"ESTIMATED","INTERVENTIONAL",[55],"NA","Brief Title: Safe Exercise for Age-Related Muscle Loss in Hospitalized Seniors\n\nSummary:\n\nThis study compares two exercise methods to help older hospital patients (age 65+) rebuild muscle strength after being diagnosed with sarcopenia (age-related muscle loss). We want to know if using special pressure cuffs during light exercise works better than traditional strength training alone.\n\nWho Can Join:\n\nHospitalized seniors with stable health conditions Excludes those with severe disabilities, dementia, or certain blood circulation problems\n\nWhat We'll Do:\n\n40 participants will be randomly assigned to either:\n\nTraditional Training Group:\n\nUses weights\u002Fbands at 65-75% max capacity Arm\u002Fleg exercises 3x\u002Fweek for 4 weeks\n\nPressure Cuff Training Group:\n\nUses special cuffs on arms\u002Fthighs during lighter exercises (20% max capacity) Same exercise frequency with controlled pressure for safety\n\nWhat We'll Measure:\n\nHandgrip strength (main test at 0\u002F4\u002F12 weeks) Walking speed, balance tests, quality of life surveys Any side effects like dizziness\u002Fnausea\n\nSafety First:\n\nDoctors will check your health before starting. Nurses will monitor every session. We use medical-grade cuffs with safe pressure limits (arm: 80-100mmHg, thigh: 150-200mmHg). You can stop anytime if uncomfortable.\n\nWhy This Matters:\n\nThis could help hospitalized seniors regain strength faster using gentler exercises. All activities are supervised by rehabilitation specialists at West China Hospital, with ethics committee approval (IRB number required).",[58],"Sarcopenia in Elderly","NOT_YET_RECRUITING","2025-05-20",{"date":62,"type":63},"2025-05-23","ACTUAL",{"date":65,"type":52},"2025-05",{"date":67,"type":52},"2025-09-10",{"name":5,"class":6}]